4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile

Base Information

Chemical Name:4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile
CAS No.:89549-70-2
Molecular Formula:C17H11N5O2
Molecular Weight:317.307
Hs Code.:
DSSTox Substance ID:DTXSID00515503
Wikidata:Q82376411

Synonyms:89549-70-2;4-(4-NITROPHENYL)-6-(PHENYLAMINO)PYRIMIDINE-5-CARBONITRILE;4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile;DTXSID00515503

Suppliers and Price of 4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:317.09127461
Heavy Atom Count:24
Complexity:471

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=NC=NC(=C2C#N)C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile

There total 6 articles about 4-Anilino-6-(4-nitrophenyl)pyrimidine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 89549-86-0
4-(p-nitrophenyl)-1-phenyl-1H-pyrazolo<3,4-d>pyrimidine

: 89549-70-2
6-anilino-4-(p-nitrophenyl)-5-pyrimidinecarbonitrile

Guidance literature:: With sodium hydroxide; In dimethyl sulfoxide; for 3h; Ambient temperature;

Reference yield:

: 5334-48-5
4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine

: 89549-70-2
6-anilino-4-(p-nitrophenyl)-5-pyrimidinecarbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / NaH (50percent in oil) / dimethylformamide / 0.17 h / 0 °C

2: 17 percent / 10percent NaOH / dimethylsulfoxide / 1 h / Ambient temperature

3: 83 percent / 50percent NaOH / dimethylsulfoxide / 3 h / Ambient temperature

With sodium hydroxide; sodium hydride; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 51130-02-0
2-benzoyloxy-2-(4-nitrophenyl)acetonitrile

: 89549-70-2
6-anilino-4-(p-nitrophenyl)-5-pyrimidinecarbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / NaH (50percent in oil) / dimethylformamide / 0.17 h / 0 °C

2: 17 percent / 10percent NaOH / dimethylsulfoxide / 1 h / Ambient temperature

3: 83 percent / 50percent NaOH / dimethylsulfoxide / 3 h / Ambient temperature

With sodium hydroxide; sodium hydride; In dimethyl sulfoxide; N,N-dimethyl-formamide;