1,2-Diphenylethyl acetate

Base Information

• Chemical Name: 1,2-Diphenylethyl acetate
• CAS No.: 24295-35-0
• Molecular Formula: C16H16 O2
• Molecular Weight: 240.302
• Hs Code.: 2915390090
• European Community (EC) Number: 246-135-0
• Nikkaji Number: J287.206D
• Mol file: 24295-35-0.mol

Synonyms:1,2-Diphenylethyl acetate;alpha-Phenylbenzeneethanol acetate;Benzeneethanol, .alpha.-phenyl-, acetate

Chemical Property of 1,2-Diphenylethyl acetate

Chemical Property:

• Vapor Pressure: 0.000212mmHg at 25°C
• Boiling Point: 351.4°Cat760mmHg
• Flash Point: 140.4°C
• PSA: 26.30000
• Density: 1.079g/cm³
• LogP: 3.53350
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 240.115029749
• Heavy Atom Count: 18
• Complexity: 250

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC(CC1=CC=CC=C1)C2=CC=CC=C2

Technology Process of 1,2-Diphenylethyl acetate

There total 33 articles about 1,2-Diphenylethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-acetoxy-1,2-diphenyl-2-nitroethane (92963-88-7) → 1-acetoxy-1,2-diphenylethane (24295-35-0)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); In benzene; for 2h; Heating;

DOI:10.1016/S0040-4020(01)97180-7

Reference yield: 71.0%

vinyl acetate (108-05-4,9003-20-7) + phenylboronic acid (98-80-6) → (E)-1,2-diphenyl-ethene (103-30-0) + 1-acetoxy-1,2-diphenylethane (24295-35-0)

Guidance literature:

With palladium diacetate; p-benzoquinone; In water; at 20 ℃; for 24h; Reagent/catalyst;

DOI:10.1002/ejoc.202101211

Reference yield: 71.0%

vinyl acetate (108-05-4,9003-20-7) + phenylboronic acid (98-80-6) → 1-acetoxy-1,2-diphenylethane (24295-35-0)

Guidance literature:

With palladium diacetate; p-benzoquinone; In water; at 25 ℃; for 24h; Reagent/catalyst;

DOI:10.1002/ejoc.202101211

upstream raw materials:

1,2-Diphenylethanol

acetic anhydride

benzaldehyde

benzylmagnesium chloride

Downstream raw materials:

1,2-Diphenylethanol

(E)-2-nitrostilbene

1-acetoxy-1,2-diphenyl-2-nitroethane

(E)-1,2-diphenyl-ethene

Refernces

• 1、 Brodzka, Anna,Koszelewski, Dominik,Ostaszewski, Ryszard,Trzepizur, Damian,Wilk, Monika. "Selective Palladium-Catalyzed α,β-Homodiarylation of Vinyl Esters in Aqueous Medium". . p. 6028 - 6036. Retrieved 2021/12/10.
• 2、 Musa, Musa M.,Bsharat, Odey,Karume, Ibrahim,Vieille, Claire,Takahashi, Masateru,Hamdan, Samir M.. "Expanding the Substrate Specificity of Thermoanaerobacter pseudoethanolicus Secondary Alcohol Dehydrogenase by a Dual Site Mutation". . p. 798 - 805. Retrieved 2018/02/21.