6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

Base Information

Chemical Name:6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS No.:89607-43-2
Molecular Formula:C14H12N4O2
Molecular Weight:268.275
Hs Code.:2934999090
DSSTox Substance ID:DTXSID601128229
Nikkaji Number:J3.328.444F,J2.631.365A
ChEMBL ID:CHEMBL2064358
Mol file:89607-43-2.mol

Synonyms:89607-43-2;6-amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile;6-amino-4-(4-hydroxyphenyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile;CHEMBL2064358;HMUNAHGDBDCYKK-UHFFFAOYSA-N;DTXSID601128229;BBL022395;STK032582;AKOS000667933;AKOS001644049;AKOS016043007;VS-07194;CS-0280156;SR-01000451719;SR-01000451719-1;Z56790118;F0837-0169;"6-Amino-4-(4-hydroxy-phenyl)-3-methyl-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile;3-Methyl-4-(4-hydroxyphenyl)-6-amino-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile;6-Amino-1,4-dihydro-4-(4-hydroxyphenyl)-3-methylpyrano[2,3-c]pyrazole-5-carbonitrile;6-amino-2,4-dihydro-4-(4-hydroxyphenyl)-3-methylpyrano [2,3-c]pyrazole-5-carbonitrile;6-AMINO-4-(4-HYDROXYPHENYL)-3-ME-1,4-DIHYDROPYRANO(2,3-C)PYRAZOLE-5-CARBONITRILE;6-amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide;6-amino-4-(4-hydroxyphenyl)-3-methyl-1H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile;6-Amino-5-cyano-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole;354554-75-9

Suppliers and Price of 6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
25mg
$ 130.00

Crysdot
6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile 95+%
1g
$ 790.00

American Custom Chemicals Corporation
6-AMINO-4-(4-HYDROXYPHENYL)-3-METHYL-1,4-DIHYDROPYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE 95.00%
10G
$ 2130.81

American Custom Chemicals Corporation
6-AMINO-4-(4-HYDROXYPHENYL)-3-METHYL-1,4-DIHYDROPYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE 95.00%
5G
$ 1496.53

American Custom Chemicals Corporation
6-AMINO-4-(4-HYDROXYPHENYL)-3-METHYL-1,4-DIHYDROPYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE 95.00%
1G
$ 970.20

Total 5 raw suppliers

Chemical Property of 6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

Chemical Property:

Melting Point:234 °C
PSA：107.95000
LogP:2.34218
XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:268.09602564
Heavy Atom Count:20
Complexity:461

Purity/Quality:

99% ^*data from raw suppliers

6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(C(=C(OC2=NN1)N)C#N)C3=CC=C(C=C3)O

Technology Process of 6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

There total 17 articles about 6-Amino-4-(4-hydroxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 141-97-9
ethyl acetoacetate

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 109-77-3
malononitrile

: 354554-75-9,89607-43-2
6-amino-2,4-dihydro-4-(4-hydroxyphenyl)-3-methylpyrano[2,3-c]pyrazole-5-carbonitrile

Guidance literature:: With hydrazine hydrate; heptakis(6-amino-6-deoxy)-β-cyclodextrin; at 20 ℃; for 0.0166667h; Neat (no solvent);
DOI:10.1016/j.tetlet.2010.04.087