2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine

Base Information

Chemical Name:2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine
CAS No.:89718-93-4
Molecular Formula:C₁₇H₁₈ClNO₃
Molecular Weight:319.788
Hs Code.:
DSSTox Substance ID:DTXSID20529440
Wikidata:Q82399860

Synonyms:89718-93-4;DTXSID20529440;2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine

Suppliers and Price of 2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:319.0975211
Heavy Atom Count:22
Complexity:343

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(O1)(C2=CC=CC=C2)C3=C(C=CC(=C3)Cl)OCCN

Technology Process of 2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine

There total 3 articles about 2-[4-Chloro-2-(2-phenyl-1,3-dioxolan-2-yl)phenoxy]ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89718-92-3
<4-chloro-2-(2-phenyl<1,3>dioxolan-2-yl)phenoxy>acetonitrile

: 89718-93-4
2-[4-Chloro-2-(2-phenyl-[1,3]dioxolan-2-yl)-phenoxy]-ethylamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 2h; Yield given; Heating;

Reference yield:

: 85-19-8
(5-chloro-2-hydroxyphenyl)phenylmethanone

: 89718-93-4
2-[4-Chloro-2-(2-phenyl-[1,3]dioxolan-2-yl)-phenoxy]-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) potassium iodide, 2.) potassium carbonate / 1.) butanone, 18 h, 2.) butanone, reflux, 1.5 h

2: 90 percent / p-toluenesulfonic acid / benzene / 7.5 h / Heating

3: lithium tetrahydroaluminate / diethyl ether / 2 h / Heating

With lithium aluminium tetrahydride; potassium carbonate; toluene-4-sulfonic acid; potassium iodide; In diethyl ether; benzene;

Reference yield:

: 58430-11-8
(2-benzoyl-4-chlorophenoxy)ethanenitrile

: 89718-93-4
2-[4-Chloro-2-(2-phenyl-[1,3]dioxolan-2-yl)-phenoxy]-ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / p-toluenesulfonic acid / benzene / 7.5 h / Heating

2: lithium tetrahydroaluminate / diethyl ether / 2 h / Heating

With lithium aluminium tetrahydride; toluene-4-sulfonic acid; In diethyl ether; benzene;