6,7-Dibromoquinoline-5,8-dione

Base Information

• Chemical Name: 6,7-Dibromoquinoline-5,8-dione
• CAS No.: 18633-05-1
• Molecular Formula: C9H3Br2NO2
• Molecular Weight: 316.9336
• NSC Number: 82128
• UNII: LBN9K78MS5
• DSSTox Substance ID: DTXSID40292366
• Nikkaji Number: J1.026.166J
• Wikidata: Q82030646
• ChEMBL ID: CHEMBL488961
• Mol file: 18633-05-1.mol

Synonyms:6,7-dibromoquinoline-5,8-dione;18633-05-1;CHEMBL488961;NSC-82128;NSC82128;LBN9K78MS5;SCHEMBL6866292;6,7-dibromo-5,8-quinolindion;6,7-dibromo-5,8-dioxoquinoline;6,7-dibromo-5,8-quinolinedione;DTXSID40292366;CPZKOUMVYNIHQE-UHFFFAOYSA-N;5,8-Quinolinedione, 6,7-dibromo-;BDBM50264041;6,7-Bis(bromanyl)quinoline-5,8-dione;PD182774;CS-0146829;FT-0777883;6,7-Dibromo-5,8-dihydro-5,8-dioxoquinoline;F82810

Chemical Property of 6,7-Dibromoquinoline-5,8-dione

Chemical Property:

• Vapor Pressure: 1.54E-05mmHg at 25°C
• Boiling Point: 365.7°Cat760mmHg
• Flash Point: 175°C
• Density: 2.256g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 316.85100
• Heavy Atom Count: 14
• Complexity: 338

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=O)C(=C(C2=O)Br)Br)N=C1

Technology Process of 6,7-Dibromoquinoline-5,8-dione

There total 10 articles about 6,7-Dibromoquinoline-5,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

5,8-quinolinedione (10470-83-4) → 6,7-Dibrom-5,8-dihydrochinolin-5,8-dion (18633-05-1)

Guidance literature:

5,8-quinolinedione; With bromine; In acetic acid; at 20 ℃; for 0.5h;

With sodium acetate; In acetic acid; for 0.0833333h; Heating;

Reference yield: 67.0%

5-amino-8-hydroxyquinoline dihydrochloride (21302-43-2) → 6,7-Dibrom-5,8-dihydrochinolin-5,8-dion (18633-05-1)

Guidance literature:

With sodium bromate; hydrogen bromide; at 50 - 60 ℃; for 0.5h;

Reference yield: 66.0%

5-amino-8-hydroxyquinoline sulphate → 6,7-Dibrom-5,8-dihydrochinolin-5,8-dion (18633-05-1)

Guidance literature:

With sodium bromate; hydrogen bromide; In water; at 50 - 60 ℃; for 0.5h;

DOI:10.14233/ajchem.2017.20220

upstream raw materials:

acrolein

2,5-dimethoxyaniline

5-amino-8-hydroxyquinoline

hydrogen bromide

Downstream raw materials:

6-anilino-7-bromo-quinoline-5,8-dione

7-Brom-6-(3,5-di-tert-butyl-4-hydroxyphenyl)-5,8-dihydrochinolin-5,8-dion

6-Brom-7-(3,5-di-tert-butyl-4-hydroxyphenyl)-5,8-dihydrochinolin-5,8-dion

7-bromo-6-(4-chloro-anilino)-quinoline-5,8-dione