3,4-Dimethyl-1H-pyrrole-2-carboxylic acid

Base Information

• Chemical Name: 3,4-Dimethyl-1H-pyrrole-2-carboxylic acid
• CAS No.: 89776-55-6
• Molecular Formula: C7H9NO2
• Molecular Weight: 139.154
• Hs Code.: 2933990090
• Mol file: 89776-55-6.mol

Synonyms:2-carboxy-3,4-dimethyl-1H-pyrrole;1H-Pyrrole-2-carboxylic acid,3,4-dimethyl;3,4-Dimethyl-pyrrol-2-carbonsaeure;3,4-dimethylpyrrole-2-carboxylic acid;

Chemical Property of 3,4-Dimethyl-1H-pyrrole-2-carboxylic acid

Chemical Property:

• Vapor Pressure: 8.93E-05mmHg at 25°C
• Boiling Point: 326.2oC at 760 mmHg
• Flash Point: 151.1oC
• PSA: 53.09000
• Density: 1.233g/cm3
• LogP: 1.32970
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3,4-Dimethyl-1H-pyrrole-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Dimethyl-1H-pyrrole-2-carboxylic acid

There total 8 articles about 3,4-Dimethyl-1H-pyrrole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dimethyl-pyrrole-2-carboxylic acid benzyl ester (954-92-7) → 3,4-dimethyl-1H-pyrrole-2-carboxylic acid (89776-55-6)

Guidance literature:

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; at 25 ℃; for 24h;

DOI:10.1016/S0022-328X(01)00931-7

Reference yield: 100.0%

3,4-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester (938-75-0) → 3,4-dimethyl-1H-pyrrole-2-carboxylic acid (89776-55-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 16h; Heating;

DOI:10.1016/j.tet.2007.08.041

Reference yield:

benzyl 4,5-dimethyl-1H-pyrrole-3-carboxylate (4868-30-8) → 3,4-dimethyl-1H-pyrrole-2-carboxylic acid (89776-55-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 19h;

DOI:10.1039/P19880001569

upstream raw materials:

3,4-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester

benzyl 4,5-dimethyl-1H-pyrrole-3-carboxylate

3,4-dimethyl-pyrrole-2-carboxylic acid benzyl ester

2-(ethoxycarbonyl)-3,4,5-trimethylpyrrole