3-[(4-Nitrophenyl)methyl]quinoline

Base Information

Chemical Name:3-[(4-Nitrophenyl)methyl]quinoline
CAS No.:89816-41-1
Molecular Formula:C16H12N2O2
Molecular Weight:264.283
Hs Code.:
DSSTox Substance ID:DTXSID90522069
Wikidata:Q82387014

Synonyms:3-[(4-Nitrophenyl)methyl]quinoline;89816-41-1;DTXSID90522069

Suppliers and Price of 3-[(4-Nitrophenyl)methyl]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 3-[(4-Nitrophenyl)methyl]quinoline

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:264.089877630
Heavy Atom Count:20
Complexity:334

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C=N2)CC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 3-[(4-Nitrophenyl)methyl]quinoline

There total 6 articles about 3-[(4-Nitrophenyl)methyl]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 5332-24-1
3-bromoquinoline

: 42766-39-2
potassium 2-(4-nitrophenyl)acetate

: 89816-41-1
3-(p-nitrobenzyl)quinoline

Guidance literature:: With bis(η3-allyl-μ-chloropalladium(II)); XPhos; In 1,3,5-trimethyl-benzene; at 140 ℃; for 5h; Inert atmosphere;
DOI:10.1021/ol201750s

Reference yield: 7.0%

: 89816-38-6
α-(p-nitrobenzyl)-β-anilinoacrolein

: 89816-41-1
3-(p-nitrobenzyl)quinoline

Guidance literature:: With aluminium trichloride; at 140 - 160 ℃; for 5h;

Reference yield:

: 104-03-0
4-nitrobenzeneacetic acid

: 89816-41-1
3-(p-nitrobenzyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / ethanol / 1.17 h / 20 °C / Inert atmosphere

2: bis(η3-allyl-μ-chloropalladium(II)); XPhos / 1,3,5-trimethyl-benzene / 5 h / 140 °C / Inert atmosphere

With bis(η3-allyl-μ-chloropalladium(II)); potassium tert-butylate; XPhos; In ethanol; 1,3,5-trimethyl-benzene;
DOI:10.1021/ol201750s