Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate

Base Information

Chemical Name:Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate
CAS No.:89861-31-4
Molecular Formula:C13H13ClO3
Molecular Weight:252.697
Hs Code.:
DSSTox Substance ID:DTXSID80710155

Synonyms:89861-31-4;Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate;DTXSID80710155

Suppliers and Price of Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate

Chemical Property:

PSA：43.37000
LogP:2.87550
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:252.0553220
Heavy Atom Count:17
Complexity:291

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C=CC1=CC=C(C=C1)Cl

Technology Process of Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate

There total 3 articles about Ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 104-88-1
4-chlorobenzaldehyde

: 89861-27-8
C₁₀H₁₇O₆P^(2-)*2K⁽¹⁺⁾

: 89861-31-4
(E)-5-(4-Chloro-phenyl)-3-oxo-pent-4-enoic acid ethyl ester

Guidance literature:: DOI:10.1016/S0040-4039(00)94110-8

Reference yield: 61.0%

: 141-97-9
ethyl acetoacetate

: 104-88-1
4-chlorobenzaldehyde

: 89861-31-4
ethyl 5-(4-chlorophenyl)-3-oxopent-4-enoate

Guidance literature:: In ethanol; for 2h; Reflux;
DOI:10.1007/s00044-011-9919-3

Reference yield:

: 65043-08-5
ethyl 4-diethoxyphosphoryl-3-oxobutanoate

: 104-88-1
4-chlorobenzaldehyde

: 89861-31-4
(E)-5-(4-Chloro-phenyl)-3-oxo-pent-4-enoic acid ethyl ester

Guidance literature:: ethyl 4-diethoxyphosphoryl-3-oxobutanoate; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 20 ℃;

4-chlorobenzaldehyde; In tetrahydrofuran; hexane; at 20 ℃; for 2.5h;
DOI:10.1016/j.molcatb.2013.09.003