4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline)

Base Information

• Chemical Name: 4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline)
• CAS No.: 57751-98-1
• Molecular Formula: C21H24 N2 O
• Molecular Weight: 320.434
• European Community (EC) Number: 260-927-3
• NSC Number: 43933
• DSSTox Substance ID: DTXSID40206448
• Nikkaji Number: J296.782K
• Wikidata: Q83080280
• Mol file: 57751-98-1.mol

Synonyms:57751-98-1;4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline);EINECS 260-927-3;4,4'-(2-FURYLMETHYLENE)BIS[N,N-DIMETHYLANILINE];NSC43933;SCHEMBL10800972;DTXSID40206448;NSC 43933;NSC-43933;AKOS024324686;2-[4,4'-Bis(dimethylamino)benzhydryl]furan;4,4'-(Furan-2-ylmethylene)bis(N,N-dimethylaniline);N-{4-[[4-(dimethylamino)phenyl](2-furyl)methyl]phenyl}-N,N-dimethylamine

Chemical Property of 4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline)

Chemical Property:

• Boiling Point: 438.2°Cat760mmHg
• Flash Point: 218.8°C
• PSA: 19.62000
• Density: 1.099g/cm³
• LogP: 4.59180
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 320.188863393
• Heavy Atom Count: 24
• Complexity: 340

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)C3=CC=CO3

Technology Process of 4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline)

There total 3 articles about 4,4'-(2-Furylmethylene)bis(N,N-dimethylaniline) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

furfural (98-01-1) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 4,4'-(furan-2-ylmethylene)bis(N,N-dimethylaniline) (57751-98-1)

Guidance literature:

With sodium iodine dichloride; In water; acetonitrile; at 20 ℃; for 6h;

DOI:10.1080/00397911.2012.680569

Reference yield:

potassium (furan-2-yl)trifluoroboranuide (166328-14-9) + bis(4-(dimethylamino)phenyl)methylium tetrafluoroborate → 4,4',4'',4'''-(furan-2,5-diylbis(methanetriyl))tetrakis(N,Ndimethylaniline) (1428869-16-2) + 4,4'-(furan-2-ylmethylene)bis(N,N-dimethylaniline) (57751-98-1)

Guidance literature:

In acetonitrile; at 20 ℃; for 2h;

DOI:10.1021/ja4017655

Reference yield:

bis(4-(dimethylamino)phenyl)methylium tetrafluoroborate + potassium (furan-3-yl)trifluoroboranuide → 4,4',4'',4'''-(furan-2,5-diylbis(methanetriyl))tetrakis(N,Ndimethylaniline) (1428869-16-2) + 4,4'-(furan-2-ylmethylene)bis(N,N-dimethylaniline) (57751-98-1)

Guidance literature:

In acetonitrile; for 2h;

DOI:10.1021/ja4017655

upstream raw materials:

furfural

N,N-dimethyl-aniline

potassium (furan-2-yl)trifluoroboranuide

Refernces

• 1、 Berionni, Guillaume,Morozova, Varvara,Heininger, Maximilian,Mayer, Peter,Knochel, Paul,Mayr, Herbert. "Electrophilic aromatic substitutions of aryltrifluoroborates with retention of the BF3- group: Quantification of the activating and directing effects of the trifluoroborate group". supporting information. p. 6317 - 6324. Retrieved 2013/05/22.
• 2、 Shanmuga,Varma. "Montmorillonite K10 clay catalysed Baeyer condensation of heterocyclic aldehydes with N,N-dimethylaniline: Synthesis and photo irradiation studies of heteroaryldiarylmethanes". . p. 1258 - 1263. Retrieved 2007/10/03.