(17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one

Base Information

• Chemical Name: (17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one
• CAS No.: 18209-21-7
• Molecular Formula: C28H45NO2
• Molecular Weight: 427.6624
• Mol file: 18209-21-7.mol

Synonyms:(3S,4aS,6aR,6bS,9R,11aR,11bR)-9-[1-(1,5-Dimethyl-piperidin-2-yl)-ethyl]-3-hydroxy-10,11b-dimethyl-1,2,3,4,4a,6,6a,6b,7,8,9,11,11a,11b-tetradecahydro-benzo[a]fluoren-5-one;

Chemical Property of (17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one

Chemical Property:

• Melting Point: 169-170°C
• PSA: 40.54000
• LogP: 5.40960

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: The bulbs of Korolkowia sewerzowii also yield this steroidal alkaloid which is precipitated by the addition of C6H6 to a petroleum ether extract of the mixed alkaloids. The base has [α]D - 84° (c 0.9, CHC13) and forms crystalline salts, e.g. the hydrobromide, m.p. 289-290°C; the perchlorate, m.p. 244-SoC; isothiocyanate, m.p. 264-SoC; oxime, m.p. 200-1 DC; methiodide, m.p. 244-SoC and semicarbazone, m.p. 190°C after softening at 160°C. The O-acetyl derivative forms a perchlorate, m.p. 178-9°C.LiAIH4 or hydrogenation over Pt yields dihydrokorseving, m.p. 218-9°C; [α]D - 87° (c 0.16, MeOH) which gives a diacetyl derivative, m.p. l33-4°C. Chromic acid oxidation furnishes korsevinone forming a perchlorate, m.p. 240°C after crystallization from H20. The structure of the alkaloid has been determined from mass spectrometry, NMR, ultraviolet and infrared spectroscopy

Technology Process of (17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one

There total 1 articles about (17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Korsevin (18209-21-7)

Guidance literature:

Korseanin, HCl, A.;

DOI:10.1007/BF00565573