2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-

Base Information

Chemical Name:2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-
CAS No.:74196-93-3
Molecular Formula:C₁₃H₂₁N₃
Molecular Weight:219.33
Hs Code.:
Nikkaji Number:J430.196J

Synonyms:74196-93-3;2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-;NSC_54562;Quinpirole,(+);SCHEMBL3425211;SCHEMBL10745904;BDBM84634;CAS_54562;PDSP1_001505;PDSP2_001489;PDSP2_001505;trans-(-)-4,4a,5,6,7,8,8a,9-octa-hydro-5-propyl-2h-pyrazolo-[3,4-g] quinoline

Suppliers and Price of 2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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price

Total 1 raw suppliers

Chemical Property of 2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-

Chemical Property:

Vapor Pressure:4.26E-06mmHg at 25°C
Boiling Point:383.9°Cat760mmHg
Flash Point:186°C
Density:1.07g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:219.173547683
Heavy Atom Count:16
Complexity:243

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCCC2C1CC3=C(C2)NN=C3
Isomeric SMILES:CCCN1CCC[C@@H]2[C@@H]1CC3=C(C2)NN=C3

Technology Process of 2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel-

There total 8 articles about 2H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR,8aR)-rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23510-95-4
4-benzoyloxycyclohexanone

: 74196-93-3,99745-18-3,112137-15-2
quinpirole

Guidance literature:: Multi-step reaction with 8 steps

2: LiAlH₄ / tetrahydrofuran / 4.75 h / Heating

3: 1.) HCl(gas), 2.) NaCNBH₄ / 1.) Et₂O, 2.) THF, MeOH, 1.5 h

4: 58 percent / CH₂Cl₂ / 15 h / 25 °C

5: 84 percent / pyridine hydrochloride chromate / CH₂Cl₂ / 6 h

6: 58 percent / toluene / 19 h / Heating

7: 58 percent / hydrazine hydrate / methanol / 15.5 h / 25 °C

8: NaCNBH₃ / methanol / 28 h

With hydrogenchloride; lithium aluminium tetrahydride; pyridine hydrochloride chromate; sodium cyanoborohydride; hydrazine hydrate; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jm00179a003

Reference yield:

: trans-(+/-)-1-cyano-6-hydroxydecahydroquinoline

: 74196-93-3,99745-18-3,112137-15-2
quinpirole

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / pyridine hydrochloride chromate / CH₂Cl₂ / 6 h

2: 58 percent / toluene / 19 h / Heating

3: 58 percent / hydrazine hydrate / methanol / 15.5 h / 25 °C

4: NaCNBH₃ / methanol / 28 h

With pyridine hydrochloride chromate; sodium cyanoborohydride; hydrazine hydrate; In methanol; dichloromethane; toluene;
DOI:10.1021/jm00179a003

Reference yield:

: trans-(+/-)-octahydro-1-cyano-6(2H)-quinolinone

: 74196-93-3,99745-18-3,112137-15-2
quinpirole

Guidance literature:: Multi-step reaction with 3 steps

1: 58 percent / toluene / 19 h / Heating

2: 58 percent / hydrazine hydrate / methanol / 15.5 h / 25 °C

3: NaCNBH₃ / methanol / 28 h

With sodium cyanoborohydride; hydrazine hydrate; In methanol; toluene;
DOI:10.1021/jm00179a003