1-Chloro-4-phenylisoquinoline-3-carboxylic acid

Base Information

Chemical Name:1-Chloro-4-phenylisoquinoline-3-carboxylic acid
CAS No.:89929-13-5
Molecular Formula:C16H10ClNO2
Molecular Weight:283.70900
Hs Code.:
DSSTox Substance ID:DTXSID80530355
Wikidata:Q82401430

Synonyms:1-Chloro-4-phenylisoquinoline-3-carboxylic acid;89929-13-5;DTXSID80530355

Suppliers and Price of 1-Chloro-4-phenylisoquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Chloro-4-phenylisoquinoline-3-carboxylic acid

Chemical Property:

Boiling Point:426.9±40.0 °C(Predicted)
PSA：50.19000
Density:1.373±0.06 g/cm3(Predicted)
LogP:4.25340
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:283.0400063
Heavy Atom Count:20
Complexity:356

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N=C(C3=CC=CC=C32)Cl)C(=O)O

Technology Process of 1-Chloro-4-phenylisoquinoline-3-carboxylic acid

There total 1 articles about 1-Chloro-4-phenylisoquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 78945-98-9
1-chloro-3-carboxymethyl-4-phenylisoquinoline

: 89929-13-5
1-cloro-3-carbossi-4-fenilisochinolina

Guidance literature:: With sodium carbonate; In water; at 105 ℃; for 20h;

Reference yield: 85.0%

: 89929-13-5
1-cloro-3-carbossi-4-fenilisochinolina

: 89928-71-2
cloruro acido della 1-cloro-3-carbossi-4-fenilisochinolina

Guidance literature:: With thionyl chloride; at 30 ℃; for 0.0833333h;

Reference yield:

: 89929-13-5
1-cloro-3-carbossi-4-fenilisochinolina

: 89928-73-4
1-Chloro-4-phenyl-isoquinoline-3-carboxylic acid 2-dimethylamino-ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / thionyl chloride / 0.08 h / 30 °C

2: 72 percent / benzene / 48 h

With thionyl chloride; In benzene;