2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide

Base Information

Chemical Name:2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide
CAS No.:89990-38-5
Molecular Formula:C₈H₅F₆N₃O
Molecular Weight:273.138
Hs Code.:2933399990
European Community (EC) Number:887-697-2
DSSTox Substance ID:DTXSID10522021
Wikidata:Q82386932
Mol file:89990-38-5.mol

Synonyms:89990-38-5;2-amino-4,6-bis(trifluoromethyl)nicotinamide;2-amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide;C8H5F6N3O;DTXSID10522021;MFCD13193070;AKOS005072867;GD-0236;CS-0257253;EN300-66704;G23265;J-507820;Z1065614838

Suppliers and Price of 2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Amino-4,6-bis(trifluoromethyl)nicotinamide
1 g
$ 343.00

SynQuest Laboratories
2-Amino-4,6-bis(trifluoromethyl)nicotinamide
500 mg
$ 228.00

Matrix Scientific
2-Amino-4,6-bis(trifluoromethyl)nicotinamide >95%
1g
$ 454.00

Matrix Scientific
2-Amino-4,6-bis(trifluoromethyl)nicotinamide >95%
500mg
$ 362.00

Crysdot
2-Amino-4,6-bis(trifluoromethyl)nicotinamide 95+%
5g
$ 844.00

Apolloscientific
2-Amino-4,6-bis(trifluoromethyl)nicotinamide
1g
$ 214.00

Apolloscientific
2-Amino-4,6-bis(trifluoromethyl)nicotinamide
500mg
$ 142.00

American Custom Chemicals Corporation
2-AMINO-4,6-BIS(TRIFLUOROMETHYL)NICOTINAMIDE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
2-AMINO-4,6-BIS(TRIFLUOROMETHYL)NICOTINAMIDE 95.00%
2.5G
$ 1147.43

American Custom Chemicals Corporation
2-AMINO-4,6-BIS(TRIFLUOROMETHYL)NICOTINAMIDE 95.00%
1G
$ 808.89

Total 6 raw suppliers

Chemical Property of 2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide

Chemical Property:

Melting Point:188-190°
PSA：82.99000
LogP:3.26570
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:1
Exact Mass:273.03368076
Heavy Atom Count:18
Complexity:328

Purity/Quality:

98%Min ^*data from raw suppliers

2-Amino-4,6-bis(trifluoromethyl)nicotinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(N=C1C(F)(F)F)N)C(=O)N)C(F)(F)F

Technology Process of 2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide

There total 2 articles about 2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 681839-63-4,89990-37-4
4,6-ditrifluoromethyl-3-oxo-2,3-dihydropyrazolo<3,4-b>pyridine

: 89990-38-5
2-amino-4,6-ditrifluoromethyl-nicotinamide

Guidance literature:: nickel Raney; In ethanol; for 8h; Heating;

Reference yield:

: 1522-22-1
1,1,1,5,5,5-hexafluoroacetylacetone

: 89990-38-5
2-amino-4,6-ditrifluoromethyl-nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / galcial acetic acid / 3 h / Heating

2: 77 percent / nickel Raney / ethanol / 8 h / Heating

With acetic acid; nickel Raney; In ethanol;