[(2-Aminophenyl)methyl]methylphosphinic acid

Base Information

Chemical Name:[(2-Aminophenyl)methyl]methylphosphinic acid
CAS No.:90043-21-3
Molecular Formula:C8H12NO2P
Molecular Weight:185.163
Hs Code.:
DSSTox Substance ID:DTXSID80533528
Wikidata:Q82406902

Synonyms:90043-21-3;[(2-Aminophenyl)methyl]methylphosphinic acid;SCHEMBL11492465;DTXSID80533528

Suppliers and Price of [(2-Aminophenyl)methyl]methylphosphinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of [(2-Aminophenyl)methyl]methylphosphinic acid

Chemical Property:

XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:185.06056562
Heavy Atom Count:12
Complexity:196

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CP(=O)(CC1=CC=CC=C1N)O

Technology Process of [(2-Aminophenyl)methyl]methylphosphinic acid

There total 1 articles about [(2-Aminophenyl)methyl]methylphosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: (2-aminobenzyl)methylphosphinic acid hydrochloride

: 90043-21-3
(2-aminobenzyl)methylphosphinic acid

Guidance literature:: With ammonium hydroxide; In ethanol; pH=3.9;

Reference yield:

: 90043-21-3
(2-aminobenzyl)methylphosphinic acid

: 90043-27-9
1-benzyl-2-methyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-sulfide

Guidance literature:: Multi-step reaction with 3 steps

1: dcc / CHCl₃ / 3 h / Heating

2: 1.) NaH / 1.) DMF, 0-5 deg C, 5 min, 2.) 40 deg C, 2 h

3: 81 percent / phosphorus pentasulfide / toluene / 1.5 h / Heating

With diphosphorus pentasulfide; sodium hydride; dicyclohexyl-carbodiimide; In chloroform; toluene;

Reference yield:

: 90043-21-3
(2-aminobenzyl)methylphosphinic acid

: 90043-23-5
1-benzyl-2-methyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: dcc / CHCl₃ / 3 h / Heating

2: 1.) NaH / 1.) DMF, 0-5 deg C, 5 min, 2.) 40 deg C, 2 h

With sodium hydride; dicyclohexyl-carbodiimide; In chloroform;