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Technology Process of Repaglinide, (-)-

Repaglinide, (-)-

Base Information
  • Chemical Name:Repaglinide, (-)-
  • CAS No.:147852-26-4
  • Molecular Formula:C27H36 N2 O4
  • Molecular Weight:452.58574
  • Hs Code.:2933399090
  • UNII:85M30X62FM
  • DSSTox Substance ID:DTXSID70163818
  • Nikkaji Number:J555.406C
  • Wikidata:Q27269656
  • ChEMBL ID:CHEMBL151767
  • Mol file:147852-26-4.mol
Repaglinide, (-)-

Synonyms:(+)-2-ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic acid;(+)-repaglinide;(-)-repaglinide;(S)-2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)-phenyl)butyl)amino)-2-oxoethyl)-benzoic acid;2-ethoxy-4-(2-(((1R)-3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid;2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid;2-ethoxy-N-(alpha-(2-methyl-1-propyl)-2-piperidinobenzyl)-4-carbamoylmethylbenzoic acid;AG-EE 388;AG-EE 388 ZW;AG-EE 623 ZW;AG-EE 624ZW;AG-EE-623-ZW;AG-EE-623ZW;AG-EE-624ZW;AGEE-623ZW;GlucoNorm;NovoNorm;Prandin;repa-glinide;repaglinide;repaglinide impurity E;repaglinide related compound E;repaglinide, (+-)-isomer

Suppliers and Price of Repaglinide, (-)-
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (R)-(-)-Repaglinide(RepaglinideImpurity)
  • 10mg
  • $ 1320.00
  • Sigma-Aldrich
  • Repaglinide impurity E European Pharmacopoeia (EP) Reference Standard
  • y0000459
  • $ 190.00
  • Sigma-Aldrich
  • Repaglinide impurity E
  • 20mg
  • $ 2240.00
  • Medical Isotopes, Inc.
  • (R)-(-)-Repaglinide(RepaglinideImpurity)
  • 5 mg
  • $ 2200.00
  • Biosynth Carbosynth
  • 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
  • 10 mg
  • $ 1638.00
  • Biosynth Carbosynth
  • 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
  • 5 mg
  • $ 900.90
  • Biosynth Carbosynth
  • 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
  • 2 mg
  • $ 495.50
  • Biosynth Carbosynth
  • 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
  • 1 mg
  • $ 272.60
  • American Custom Chemicals Corporation
  • (R)-(-)-REPAGLINIDE 95.00%
  • 100MG
  • $ 269.85
Total 10 raw suppliers
Chemical Property of Repaglinide, (-)-
Chemical Property:
  • Vapor Pressure:0mmHg at 25°C 
  • Boiling Point:672.938°C at 760 mmHg 
  • PKA:4.19±0.10(Predicted) 
  • Flash Point:360.78°C 
  • PSA：82.36000 
  • Density:1.138g/cm3 
  • LogP:6.12520 
  • XLogP3:5.2
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:10
  • Exact Mass:452.26750763
  • Heavy Atom Count:33
  • Complexity:619
Purity/Quality:

97% *data from raw suppliers

(R)-(-)-Repaglinide(RepaglinideImpurity) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
  • Isomeric SMILES:CCOC1=C(C=CC(=C1)CC(=O)N[C@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
  • Uses The R-enantiomer showed only weak hypoglycemic activity. Repaglinide impurity.
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