Benzenesulfonamide,N,N'-1,5-naphthalenediylbis[4-methyl-

Base Information

• Chemical Name: Benzenesulfonamide,N,N'-1,5-naphthalenediylbis[4-methyl-
• CAS No.: 57159-76-9
• Molecular Formula: C24H22 N2 O4 S2
• Molecular Weight: 466.5725
• Mol file: 57159-76-9.mol

Synonyms:Naphthalene,1,5-bis(p-tolylsulfonamido)- (4CI); p-Toluenesulfonamide,N,N'-1,5-naphthylenebis- (6CI); 1,5-Di-p-toluenesulfamidonaphthalene; NSC144469

Chemical Property of Benzenesulfonamide,N,N'-1,5-naphthalenediylbis[4-methyl-

Chemical Property:

• Boiling Point: 671.1°Cat760mmHg
• Flash Point: 359.6°C
• Density: 1.395g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonamide,N,N'-1,5-naphthalenediylbis[4-methyl-

There total 3 articles about Benzenesulfonamide,N,N'-1,5-naphthalenediylbis[4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

p-toluenesulfonyl chloride (98-59-9) + 1,5-naphthalenediamine (2243-62-1) → 1,5-bis(p-toluenesulfonamido)naphthalene (57159-76-9)

Guidance literature:

With pyridine; In toluene; at 100 ℃; for 2h; Inert atmosphere;

DOI:10.1002/asia.201801656

Reference yield:

1-Nitronaphthalene (86-57-7) → 1,5-bis(p-toluenesulfonamido)naphthalene (57159-76-9)

Guidance literature:

Multi-step reaction with 3 steps

1: KNO₃; concentrated H₂SO₄ / 0 °C

2: iron; iron (II)-sulfate; water

3: ethanol; pyridine

With pyridine; ethanol; sulfuric acid; water; iron; iron(II) sulfate; potassium nitrate;

DOI:10.1039/jr9450000202

Reference yield:

1,5-dinitronaphthalene (605-71-0) → 1,5-bis(p-toluenesulfonamido)naphthalene (57159-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: iron; iron (II)-sulfate; water

2: ethanol; pyridine

With pyridine; ethanol; water; iron; iron(II) sulfate;

DOI:10.1039/jr9450000202

upstream raw materials:

p-toluenesulfonyl chloride

1,5-naphthalenediamine

1-Nitronaphthalene

1,5-dinitronaphthalene

Downstream raw materials:

1.5-Dichlor-4.8-bis-tosylamino-naphthalin

1.3.5.7-Tetrachlor-4.8-bis-tosylamino-naphthalin

1,2,4,5,6,8-hexachloronaphthalene

1,3,5,7-tetrachloronaphthalene

Refernces

• 1、 Li, Xuting,Gong, Xue,Zhao, Miao,Song, Guoyong,Deng, Jian,Li, Xingwei. "Rh(III)-catalyzed oxidative olefination of N-(1-naphthyl)sulfonamides using activated and unactivated alkenes". supporting information; experimental part. p. 5808 - 5811. Retrieved 2011/12/22.