2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid

Base Information

Chemical Name:2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid
CAS No.:116759-27-4
Molecular Formula:C₂₀H₁₄BrNO₄S
Molecular Weight:444.305
Hs Code.:
Wikidata:Q76390013

Synonyms:2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid;5-Thiazoleacetic acid, 2-(2-(1,3-benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-;116759-27-4;C20H14BrNO4S;C20-H14-Br-N-O4-S;LS-150654

Suppliers and Price of 2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid

Chemical Property:

Vapor Pressure:2.07E-18mmHg at 25°C
Boiling Point:661.7°C at 760 mmHg
Flash Point:354°C
Density:1.613g/cm³
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:442.98269
Heavy Atom Count:27
Complexity:554

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)C=CC3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Br
Isomeric SMILES:C1OC2=C(O1)C=C(C=C2)/C=C/C3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Br

Technology Process of 2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid

There total 3 articles about 2-(2-(1,3-Benzodioxol-5-yl)ethenyl)-4-(4-bromophenyl)-5-thiazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-4-(4-bromo-phenyl)-thiazol-5-yl]-acetic acid ethyl ester

: 116759-27-4
[2-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-4-(4-bromo-phenyl)-thiazol-5-yl]-acetic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; at 50 ℃; for 1h; Yield given;

Reference yield:

: 35158-41-9
3-bromo-4-(4-bromophenyl)-4-oxobutanoic acid

: 116759-27-4
[2-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-4-(4-bromo-phenyl)-thiazol-5-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / Heating

2: KOH / ethanol; H₂O / 1 h / 50 °C

With potassium hydroxide; In ethanol; water;

Reference yield:

: 99661-62-8
(E)-3-Benzo[1,3]dioxol-5-yl-thioacrylamide

: 116759-27-4
[2-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-4-(4-bromo-phenyl)-thiazol-5-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / Heating

2: KOH / ethanol; H₂O / 1 h / 50 °C

With potassium hydroxide; In ethanol; water;