4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile

Base Information

Chemical Name:4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile
CAS No.:90179-01-4
Molecular Formula:C₂₁H₁₄BrNO₃
Molecular Weight:408.251
Hs Code.:
DSSTox Substance ID:DTXSID20531109
Wikidata:Q82402711

Synonyms:90179-01-4;DTXSID20531109;4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile

Suppliers and Price of 4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:407.01571
Heavy Atom Count:26
Complexity:489

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1COC2=C(C=C(C=C2)Br)C=O)OC3=CC=C(C=C3)C#N

Technology Process of 4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile

There total 6 articles about 4-{4-[(4-Bromo-2-formylphenoxy)methyl]phenoxy}benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 90178-74-8
4-(4-(chloromethyl)phenoxy)benzonitrile

: 1761-61-1
5-bromosalicyclaldehyde

: 90179-01-4
4-<4-(4-Brom-2-formylphenoxymethyl)phenoxy>benzonitril

Guidance literature:: DOI:10.1002/jlac.198419840302

Reference yield:

: 767-00-0
4-cyanophenol

: 90179-01-4
4-<4-(4-Brom-2-formylphenoxymethyl)phenoxy>benzonitril

Guidance literature:: Multi-step reaction with 4 steps

1: K₂CO₃ / dimethylformamide / 3 h / 155 - 160 °C

2: 89 percent / sodium tetrahydroborate / H₂O; methanol / 0.5 h

3: 85 percent / pyridine, thionylchloride / diethyl ether / 3 h / Ambient temperature

4: 62 percent

With pyridine; sodium tetrahydroborate; thionyl chloride; potassium carbonate; In methanol; diethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1002/jlac.198419840302

Reference yield:

: 1194-02-1,143234-87-1
4-fluorobenzonitrile

: 90179-01-4
4-<4-(4-Brom-2-formylphenoxymethyl)phenoxy>benzonitril

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / K₂CO₃ / dimethylformamide / 3 h / 155 - 160 °C

2: 89 percent / sodium tetrahydroborate / H₂O; methanol / 0.5 h

3: 85 percent / pyridine, thionylchloride / diethyl ether / 3 h / Ambient temperature

4: 62 percent

With pyridine; sodium tetrahydroborate; thionyl chloride; potassium carbonate; In methanol; diethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1002/jlac.198419840302