4-BROMOMETHYL-5,5-DIMETHYL-2-OXO-2,5-DIHYDRO-FURAN-3-CARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 4-BROMOMETHYL-5,5-DIMETHYL-2-OXO-2,5-DIHYDRO-FURAN-3-CARBOXYLIC ACID ETHYL ESTER
• CAS No.: 90261-67-9
• Molecular Formula: C₁₀H₁₃BrO₄
• Molecular Weight: 277.115
• Mol file: 90261-67-9.mol

Synonyms:2-ethoxycarbonyl-3-bromomethyl-4,4-dimethyl-2-buten-4-olide;2-Ethoxycarbonyl-2-benzoylamino-ethansulfonsaeure-diethylamid;2-Quinazolinecarboxylic acid,1,4-dihydro-1-methyl-4-oxo-,ethyl ester;2-ethoxycarbonyl-1-methyl-4(1H)-quinazolinone;

Chemical Property of 4-BROMOMETHYL-5,5-DIMETHYL-2-OXO-2,5-DIHYDRO-FURAN-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 2.44E-05mmHg at 25°C
• Boiling Point: 359.1oC at 760 mmHg
• Flash Point: 171oC
• PSA: 52.60000
• Density: 1.44g/cm3
• LogP: 1.57640

Purity/Quality:

99% ^*data from raw suppliers

ETHYL 4-(BROMOMETHYL)-5,5-DIMETHYL-2-OXO-2,5-DIHYDROFURAN-3-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-BROMOMETHYL-5,5-DIMETHYL-2-OXO-2,5-DIHYDRO-FURAN-3-CARBOXYLIC ACID ETHYL ESTER

There total 1 articles about 4-BROMOMETHYL-5,5-DIMETHYL-2-OXO-2,5-DIHYDRO-FURAN-3-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4,5,5-trimethyl-2-oxo-2,5-dihydro-furan-3-carboxylic acid ethyl ester (13156-09-7) → 2-ethoxycarbonyl-3-bromomethyl-4,4-dimethyl-2-buten-4-olide (90261-67-9)

Guidance literature:

With bromine; In tetrachloromethane; for 10h; Heating;

DOI:10.1007/BF00508661

Reference yield:

2-ethoxycarbonyl-3-bromomethyl-4,4-dimethyl-2-buten-4-olide (90261-67-9) → 2-ethoxycarbonyl-3-formyl-4,4-dimethyl-2-buten-4-olide 2,4-dinitrophenylhydrazone (93271-52-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / DMSO / 20 h / 75 - 80 °C

2: 90 percent / conc. H₂SO₄ / aq. ethanol

With sulfuric acid; dimethyl sulfoxide; In ethanol;

DOI:10.1007/BF00508661

upstream raw materials:

4,5,5-trimethyl-2-oxo-2,5-dihydro-furan-3-carboxylic acid ethyl ester

Downstream raw materials:

2-ethoxycarbonyl-3-formyl-4,4-dimethyl-2-buten-4-olide 2,4-dinitrophenylhydrazone