5-Cyano-2-(methylsulphonyl)benzotrifluoride

Base Information

• Chemical Name: 5-Cyano-2-(methylsulphonyl)benzotrifluoride
• CAS No.: 904311-38-2
• Molecular Formula: C9H6F3NO2S
• Molecular Weight: 249.213
• Hs Code.: 2926907090
• Mol file: 904311-38-2.mol

Synonyms:4-Methansulfonyl-2-nitro-phenol;2-nitro-4-methylsulphonyl-phenol;4-Hydroxy-3-nitrophenylmethylsulfon;4-(Methylsulfonyl)-2-nitrophenol;2-nitro-4-methylsulfonylphenol;4-methanesulfonyl-3-trifluoromethyl-benzonitrile;Methyl-<3-nitro-4-hydroxy-phenyl>-sulfon;4-Methanesulfonyl-2-nitro-phenol;4-(Methylsulphonyl)-2-nitrophenol;

Chemical Property of 5-Cyano-2-(methylsulphonyl)benzotrifluoride

Chemical Property:

• Vapor Pressure: 5.38E-06mmHg at 25°C
• Boiling Point: 380.6oC at 760 mmHg
• Flash Point: 184oC
• PSA: 66.31000
• Density: 1.48g/cm3
• LogP: 3.06138

Purity/Quality:

4-(Methylsulfonyl)-3-(trifluoromethyl)benzonitrile 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Cyano-2-(methylsulphonyl)benzotrifluoride

There total 1 articles about 5-Cyano-2-(methylsulphonyl)benzotrifluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Fluoro-3-(trifluoromethyl)benzonitrile (67515-59-7) + sodium methansulfinate (20277-69-4) → 4-(methylsulfonyl)-3-(trifluoromethyl)benzonitrile (904311-38-2)

Guidance literature:

In dimethyl sulfoxide; at 80 ℃; for 22h;

Reference yield:

4-(methylsulfonyl)-3-(trifluoromethyl)benzonitrile (904311-38-2) → 4-Methanesulfonyl-3-trifluoromethyl-benzylamine (1057260-42-0)

Guidance literature:

With ammonia; hydrogen; nickel; In methanol; for 2h;

upstream raw materials:

4-Fluoro-3-(trifluoromethyl)benzonitrile

sodium methansulfinate

Downstream raw materials:

4-Methanesulfonyl-3-trifluoromethyl-benzylamine