2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano-

Base Information

Chemical Name:2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano-
CAS No.:904311-41-7
Molecular Formula:C7H4ClN3O2
Molecular Weight:197.581
Hs Code.:2933399090
Mol file:904311-41-7.mol

Synonyms:4-amino-6-chloro-5-cyanopicolinic acid;4-amino-6-chloro-5-cyano-pyridine-2-carboxylic acid;

Suppliers and Price of 2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-6-chloro-5-cyanopicolinicacid 95+%
1g
$ 772.00

Chemenu
4-amino-6-chloro-5-cyanopicolinicacid 95%
1g
$ 729.00

American Custom Chemicals Corporation
4-AMINO-6-CHLORO-5-CYANOPICOLINIC ACID 95.00%
5MG
$ 501.13

Alichem
4-Amino-6-chloro-5-cyanopicolinicacid
1g
$ 998.00

Total 6 raw suppliers

Chemical Property of 2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano-

Chemical Property:

PSA：100.00000
LogP:1.46828
Storage Temp.:2-8°C

Purity/Quality:

95% ^*data from raw suppliers

4-Amino-6-chloro-5-cyanopicolinicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano-

There total 3 articles about 2-Pyridinecarboxylic acid, 4-amino-6-chloro-5-cyano- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 917102-32-0
4-amino-6-chloro-5-cyanopyridine-2-carboxylic acid methyl ester

: 904311-41-7
4-amino-6-chloro-5-cyanopyridine-2-carboxylic acid

Guidance literature:: 4-amino-6-chloro-5-cyanopyridine-2-carboxylic acid methyl ester; With methanol; sodium hydroxide; water; at 20 ℃; for 2h;

With hydrogenchloride; In water; pH=2;

Reference yield:

: 102291-59-8
4-amino-2-chloro-6-hydroxynicotinonitrile

: 904311-41-7
4-amino-6-chloro-5-cyanopyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂ / 6 h / 20 °C

2: PdCl₂(dppf); Et₃N / 16 h / 20 °C / 3102.89 Torr

3: aq. NaOH / methanol / 2 h / 20 °C

With pyridine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide; triethylamine; In methanol; dichloromethane;
DOI:10.1021/jm060465l

Reference yield:

: 904311-40-6
trifluoromethanesulfonic acid 4-amino-6-chloro-5-cyanopyridin-2-yl ester

: 904311-41-7
4-amino-6-chloro-5-cyanopyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: PdCl₂(dppf); Et₃N / 16 h / 20 °C / 3102.89 Torr

2: aq. NaOH / methanol / 2 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide; triethylamine; In methanol;
DOI:10.1021/jm060465l