10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid

Base Information

Chemical Name:10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid
CAS No.:67578-42-1
Molecular Formula:C17H14O4
Molecular Weight:282.2907
Hs Code.:
DSSTox Substance ID:DTXSID60986937
ChEMBL ID:CHEMBL10799

Synonyms:10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid;Dibenz(b,f)oxepin-2-acetic acid, 10,11-dihydro-alpha-methyl-11-oxo-;67578-42-1;CHEMBL10799;SCHEMBL11339446;DTXSID60986937;HHMVMSNPBYGGOD-UHFFFAOYSA-N;LS-61590;2-(10,11-dihydro-11-oxo dibenzo[b,f]oxepin-2-yl)-propionic acid;2-(11-Oxo-10,11-dihydrodibenzo[b,f]oxepin-2-yl)propanoic acid

Suppliers and Price of 10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid

Chemical Property:

Vapor Pressure:1.75E-11mmHg at 25°C
Boiling Point:516.3°Cat760mmHg
Flash Point:195.2°C
Density:1.306g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:282.08920892
Heavy Atom Count:21
Complexity:419

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)OC3=CC=CC=C3CC2=O)C(=O)O

Technology Process of 10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid

There total 6 articles about 10,11-Dihydro-alpha-methyl-11-oxodibenz(b,f)oxepin-2-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 78430-80-5
dl-2-[4-(2'-carboxymethylphenoxy)phenyl]propionic acid

: 67578-42-1
2-(10,11-dihydro-11-oxodibenzo[b,f]oxepin-2-yl)-propionic acid

Guidance literature:: With PPA; at 130 ℃; for 0.5h;
DOI:10.1021/jm00351a012

Reference yield:

: ethyl 2-(10,11-dihydro-11-oxodibenzo[b,f]oxepin-2-yl)-propionate

: 67578-42-1
2-(10,11-dihydro-11-oxodibenzo[b,f]oxepin-2-yl)-propionic acid

Guidance literature:: With potassium hydroxide; In ethanol; water;

Reference yield:

: 2142-70-3
2-iodoacetophenone

: 67578-42-1
2-(10,11-dihydro-11-oxodibenzo[b,f]oxepin-2-yl)-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: K₂CO₃, Cu, pyridine / 3 h / 140 - 150 °C

2: S / 5 h / 140 - 150 °C

3: aq. H₂SO₄, AcOH / 6 h / Heating

4: 70 percent / PPA / 0.5 h / 130 °C

With pyridine; sulfuric acid; copper; potassium carbonate; sulfur; acetic acid;
DOI:10.1021/jm00351a012