5-Pyrimidinecarboxylic acid, 2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro- 2H-pyrido[4,3-b]indol-2-yl]-, methyl ester

Base Information

Chemical Name:5-Pyrimidinecarboxylic acid, 2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro- 2H-pyrido[4,3-b]indol-2-yl]-, methyl ester
CAS No.:907566-73-8
Molecular Formula:C28H29N5O4
Molecular Weight:499.569
Hs Code.:

5-Pyrimidinecarboxylic acid,
2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro-
2H-pyrido[4,3-b]indol-2-yl]-, methyl ester

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Chemical Property of 5-Pyrimidinecarboxylic acid, 2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro- 2H-pyrido[4,3-b]indol-2-yl]-, methyl ester

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Technology Process of 5-Pyrimidinecarboxylic acid, 2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro- 2H-pyrido[4,3-b]indol-2-yl]-, methyl ester

There total 1 articles about 5-Pyrimidinecarboxylic acid, 2-[8-[3-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-1,3,4,5-tetrahydro- 2H-pyrido[4,3-b]indol-2-yl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 907564-62-9
methyl 2-(8-bromo-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)pyrimidine-5-carboxylate

: 380430-68-2
3-(tert-butoxycarbonylamino)phenylboronic acid

: 907566-73-8
methyl 2-{8-[3-(tert-butyloxycarbonylamino)phenyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl}pyrimidine-5-carboxylate

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; for 5 - 6h; Heating / reflux;