3-(4-Dimethylaminobenzylidenyl)-2-indolinone

Base Information

Chemical Name:3-(4-Dimethylaminobenzylidenyl)-2-indolinone
CAS No.:90828-16-3
Molecular Formula:C17H16N2O
Molecular Weight:264.327
Hs Code.:
UNII:QTW8MQ534B
Nikkaji Number:J3.036.273J
Wikidata:Q27077086
Pharos Ligand ID:S7Y4CC6R18CR
ChEMBL ID:CHEMBL296455

Synonyms:3-(4-dimethylaminobenzylidene)-1,3-dihydroindol-2-one;SU 4312;SU-4312;SU4312

Suppliers and Price of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:264.126263138
Heavy Atom Count:20
Complexity:394

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O
Isomeric SMILES:CN(C)C1=CC=C(C=C1)/C=C/2\C3=CC=CC=C3NC2=O

Technology Process of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone

There total 4 articles about 3-(4-Dimethylaminobenzylidenyl)-2-indolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 59-48-3
2-oxoindole

: 100-10-7
4-dimethylamino-benzaldehyde

: 90828-16-3,5812-07-7
(Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one

Guidance literature:: With sodium hydroxide; In ethanol; for 2h;
DOI:10.1248/cpb.c17-00301

Reference yield: 50.0%

: 90828-16-3,5812-07-7
(Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one

Guidance literature:: With pyrrolidine; In ethanol; at 80 ℃; for 1h;

Reference yield:

: 59-48-3
2-oxoindole

: 100-10-7
4-dimethylamino-benzaldehyde

: 90828-16-3,5812-07-7
(Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one

: 40811-67-4,5812-07-7
(E)-3-(4-(dimethylamino)benzylidene)indolin-2-one

Guidance literature:: With hydrogenchloride; acetic acid; In water; for 3h; Overall yield = 90 %; Reflux; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b00571