3-Methoxycholestan-2-one

Base Information

Chemical Name:3-Methoxycholestan-2-one
CAS No.:5788-90-9
Molecular Formula:C₂₈H₄₈O₂
Molecular Weight:416.688
Hs Code.:
NSC Number:118129,118127
DSSTox Substance ID:DTXSID10973478

Synonyms:3-methoxycholestan-2-one;5788-90-9;NSC118127;DTXSID10973478;NSC118129;NSC-118127;NSC-118129

Suppliers and Price of 3-Methoxycholestan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Methoxycholestan-2-one

Chemical Property:

Vapor Pressure:8.93E-10mmHg at 25°C
Boiling Point:490.7°Cat760mmHg
Flash Point:163.4°C
Density:0.99g/cm³
XLogP3:8.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:416.365430770
Heavy Atom Count:30
Complexity:626

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CC(=O)C(C4)OC)C)C

Technology Process of 3-Methoxycholestan-2-one

There total 7 articles about 3-Methoxycholestan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 76761-37-0
3α-methoxy-5α-cholestan-2-one

: 5788-90-9
3β-methoxy-5α-cholestan-2-one

Guidance literature:: With potassium hydroxide; In methanol; for 3h; Ambient temperature;
DOI:10.1016/0039-128X(80)90102-6

Reference yield:

: 13901-19-4,15910-23-3,570-73-0
cholest-2-ene

: 5788-90-9
3β-methoxy-5α-cholestan-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: 78 percent / I₂, KIO₃ / 2.5 h / 62 °C

2: 96 percent / NaOH / methanol; tetrahydrofuran / 2 h / Heating

3: 56 percent / p-toluenesulfonic acid / 12 h / 32 °C

4: 91 percent / CrO₃, aq. H₂SO₄ / acetone / 0.03 h / Ambient temperature

5: 51 percent / 4percent KOH / methanol / 3 h / Ambient temperature

With chromium(VI) oxide; potassium iodate; potassium hydroxide; sodium hydroxide; sulfuric acid; iodine; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; acetone;
DOI:10.1016/0039-128X(80)90102-6

Reference yield:

: 76761-36-9
3α-methoxy-5α-cholestan-2β-ol

: 5788-90-9
3β-methoxy-5α-cholestan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / CrO₃, aq. H₂SO₄ / acetone / 0.03 h / Ambient temperature

2: 51 percent / 4percent KOH / methanol / 3 h / Ambient temperature

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; In methanol; acetone;
DOI:10.1016/0039-128X(80)90102-6