7-oxostaurosporine

Base Information

• Chemical Name: 7-oxostaurosporine
• CAS No.: 141196-69-2
• Molecular Formula: C28H24 N4 O4
• Molecular Weight: 480.522
• Mol file: 141196-69-2.mol

Synonyms:9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonine-1,3(2H)-dione,10,11,12,13-tetrahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9a,10b,11b,13a)]-; 7-Oxostaurosporine; BMY41950; RK 1409

Chemical Property of 7-oxostaurosporine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 90.28000
• Density: 1.62g/cm³
• LogP: 4.14100

Purity/Quality:

98% ^*data from raw suppliers

7-Oxostaurosporine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumour cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties. 7-Oxostaurosporine is an oxidized and highly fluorescent analogue of Antibiotics UCN-01 and UCN-02.