2-[(3-cyanophenyl)amino]acetic Acid

Base Information

Chemical Name:2-[(3-cyanophenyl)amino]acetic Acid
CAS No.:91192-27-7
Molecular Formula:C9H8N2O2
Molecular Weight:176.175
Hs Code.:
European Community (EC) Number:859-951-2
DSSTox Substance ID:DTXSID80443956
Nikkaji Number:J796.638E

Synonyms:2-[(3-cyanophenyl)amino]acetic Acid;91192-27-7;2-(3-cyanoanilino)acetic acid;2-((3-cyanophenyl)amino)acetic acid;n-(3-cyanophenyl)glycine;SCHEMBL3836565;DTXSID80443956;2-((3-cyanophenyl)amino)aceticacid;AKOS009235004;AS-83914;CS-0165922;E79147;EN300-104118;Z359506264;2-((3-cyanophenyl)amino)acetic acid? (Dabigatran Impurity pound(c)

Suppliers and Price of 2-[(3-cyanophenyl)amino]acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 2-[(3-cyanophenyl)amino]acetic Acid

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:176.058577502
Heavy Atom Count:13
Complexity:231

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)NCC(=O)O)C#N

Technology Process of 2-[(3-cyanophenyl)amino]acetic Acid

There total 4 articles about 2-[(3-cyanophenyl)amino]acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 92316-76-2
ethyl 2-(3-cyanophenylamino)acetate

: 91192-27-7
2-(3-cyanophenylamino)acetic acid

Guidance literature:: ethyl 2-(3-cyanophenylamino)acetate; With lithium hydroxide monohydrate; water; In tetrahydrofuran; for 15h;

With hydrogenchloride; In tetrahydrofuran; water; pH=3;

Reference yield:

: 194162-74-8
tert-butyl N-(3-cyanophenyl)glycinate

: 91192-27-7
2-(3-cyanophenylamino)acetic acid

Guidance literature:: With methoxybenzene; trifluoroacetic acid;
DOI:10.1016/0960-894X(95)00563-9

Reference yield:

: 2237-30-1
m-cyanoaniline

: 91192-27-7
2-(3-cyanophenylamino)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / K₂CO₃ / dimethylformamide / 16 h / 80 °C

2: TFA / CH₂Cl₂; various solvent(s) / 24 h / Ambient temperature

With potassium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm970020k