12,12a-dihydro-11H-benzo[7,8]fluorantheno[1,10b-b]oxirene-11,12-diol

Base Information

• Chemical Name: 12,12a-dihydro-11H-benzo[7,8]fluorantheno[1,10b-b]oxirene-11,12-diol
• CAS No.: 151378-31-3
• Molecular Formula: C₂₀H₁₄O₃
• Molecular Weight: 302.329
• Mol file: 151378-31-3.mol

Synonyms:

Chemical Property of 12,12a-dihydro-11H-benzo[7,8]fluorantheno[1,10b-b]oxirene-11,12-diol

Chemical Property:

• Vapor Pressure: 3.84E-15mmHg at 25°C
• Boiling Point: 597.9°Cat760mmHg
• Flash Point: 315.4°C
• Density: 1.55g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12,12a-dihydro-11H-benzo[7,8]fluorantheno[1,10b-b]oxirene-11,12-diol

There total 5 articles about 12,12a-dihydro-11H-benzo[7,8]fluorantheno[1,10b-b]oxirene-11,12-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

r-6-bromo-t-4,c-5,t-6a-trihydroxy-4,5,6,6a-tetrahydrobenzofluoranthene (138857-20-2) → trans-4,5-dihydroxy-syn-6,6a-epoxy-4,5,6,6a-tetrahydrobenzofluoranthene (138857-19-9,138921-94-5,151378-31-3,151378-32-4)

Guidance literature:

With Amberlite IRA-400; In tetrahydrofuran; for 2.5h; Ambient temperature;

DOI:10.1021/jo00032a034

Reference yield: 95.0%

trans-4,5-dihydro-4,5-dihydroxybenzofluoranthene (106542-80-7,151258-40-1) → trans-4,5-dihydroxy-anti-6,6a-epoxy-4,5,6,6a-tetrahydrobenzofluoranthene (138857-19-9,138921-94-5,151378-31-3,151378-32-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; for 2h; Ambient temperature;

DOI:10.1021/jo00032a034

Reference yield:

benzofluoranthene-4,5-dione (106521-02-2) → trans-4,5-dihydroxy-anti-6,6a-epoxy-4,5,6,6a-tetrahydrobenzofluoranthene (138857-19-9,138921-94-5,151378-31-3,151378-32-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) AgNO₃, 2) KBH₄, air / 1) aq. EtOH, 15 min

2: 95 percent / mCPBA / tetrahydrofuran / 2 h / Ambient temperature

With potassium borohydride; air; silver nitrate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran;

DOI:10.1021/jo00032a034

upstream raw materials:

trans-4,5-dihydro-4,5-dihydroxybenzofluoranthene

benzofluoranthene-4,5-dione

r-6-bromo-t-4,c-5,t-6a-trihydroxy-4,5,6,6a-tetrahydrobenzofluoranthene

Refernces