(6-Chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol

Base Information

• Chemical Name: (6-Chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol
• CAS No.: 76919-42-1
• Molecular Formula: C6H7ClN2OS
• Molecular Weight: 190.653
• NSC Number: 332709
• DSSTox Substance ID: DTXSID70318563
• Wikidata: Q82074369

Synonyms:76919-42-1;NSC 332709;(6-chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol;NSC332709;DTXSID70318563;AKOS004909141;NSC-332709

Chemical Property of (6-Chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol

Chemical Property:

• Vapor Pressure: 3.25E-08mmHg at 25°C
• Boiling Point: 431.6°Cat760mmHg
• Flash Point: 214.8°C
• Density: 1.75g/cm³
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 189.9967617
• Heavy Atom Count: 11
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CSC2=NC(=C(N21)CO)Cl

Technology Process of (6-Chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol

There total 1 articles about (6-Chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-diidro-5-formil-6-cloroimidazo<2,1-b>tiazolo (75224-65-6) → 2,3-dihydro-5-hydroxymethyl-6-chloroimidazo<2,1-b>thiazole (76919-42-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; 1.) 3 h 15 min, r.t; 2.) 1 h, reflux;

Reference yield:

2,3-dimethoxy-5-methylbenzene-1,4-diol (3066-90-8) + 2,3-dihydro-5-hydroxymethyl-6-chloroimidazo<2,1-b>thiazole (76919-42-1) → 2-(6-chloro-2,3-dihydro-imidazo[2,1-b]thiazol-5-ylmethyl)-5,6-dimethoxy-3-methyl-benzene-1,4-diol

Guidance literature:

With boron trifluoride diethyl etherate; In 1,4-dioxane; at 20 ℃; for 10h;

DOI:10.1016/j.bmc.2004.08.012

Reference yield:

2,3-dihydro-5-hydroxymethyl-6-chloroimidazo<2,1-b>thiazole (76919-42-1) + 1-isocyanato-3-trifluoromethyl-benzene (329-01-1) → 2,3-Dihydro-6-chloroimidazo<2,1-b>thiazol-5-ylmethyl m-Trifluoromethylphenylcarbamate (123772-54-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 1h; Yield given; Ambient temperature;

upstream raw materials:

2,3-diidro-5-formil-6-cloroimidazo<2,1-b>tiazolo

Downstream raw materials:

2,3-Dihydro-6-chloroimidazo<2,1-b>thiazol-5-ylmethyl m-Trifluoromethylphenylcarbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 76919-42-1 (6-chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send