N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea

Base Information

Chemical Name:N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea
CAS No.:66203-98-3
Molecular Formula:C20H29N3O5
Molecular Weight:391.4614
Hs Code.:
DSSTox Substance ID:DTXSID20984691
Nikkaji Number:J87.667D
ChEMBL ID:CHEMBL289841

Synonyms:BRN 1668358;N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea;Urea, 1-(4,7-dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-3-methyl-;66203-98-3;CHEMBL289841;SCHEMBL11537505;DTXSID20984691;LS-159895;1-[4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)benzofuran-5-yl]-3-methylurea;N-(4,7-Dimethoxy-6-{[1-(piperidin-1-yl)propan-2-yl]oxy}-1-benzofuran-5-yl)-N'-methylcarbamimidic acid

Suppliers and Price of N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea

Chemical Property:

Vapor Pressure:5.33E-11mmHg at 25°C
Boiling Point:522.1°Cat760mmHg
Flash Point:269.6°C
Density:1.196g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:391.21072103
Heavy Atom Count:28
Complexity:502

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CN1CCCCC1)OC2=C(C3=C(C=CO3)C(=C2NC(=O)NC)OC)OC

Technology Process of N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea

There total 7 articles about N-(4,7-Dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl)-N'-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 66203-97-2
N-<4,7-dimethoxy-6-<(1-methyl-2-piperidinocarbonyl)ethoxy>-5-benzofuranyl>-N'-methylurea

: 66203-98-3
N-<4,7-dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl>-N'-methylurea

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;
DOI:10.1021/jm00134a007

Reference yield: 50.0%

: 66203-98-3
N-<4,7-dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl>-N'-methylurea

Guidance literature:

Reference yield:

: 52631-79-5
N-(4,7-dimethoxy-6-hydroxy-5-benzofuranyl)acetamide

: 66203-98-3
N-<4,7-dimethoxy-6-(1-methyl-2-piperidinoethoxy)-5-benzofuranyl>-N'-methylurea

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / HCl / ethanol / 20 h / Heating

2: 89 percent / CHCl₃ / 2 h / Ambient temperature

3: 41 percent / K₂CO₃ / acetonitrile / 6 h / Heating

4: 50 percent / LiAlH₄ / tetrahydrofuran / 4 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; ethanol; chloroform; acetonitrile;
DOI:10.1021/jm00134a007