2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid

Base Information

Chemical Name:2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid
CAS No.:91574-45-7
Molecular Formula:C12H9NO4
Molecular Weight:231.208
Hs Code.:
European Community (EC) Number:819-590-3
Nikkaji Number:J2.412.529G

Synonyms:91574-45-7;2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid;4-Maleimidophenylacetic Acid;2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetic acid;2-[4-(2,5-dioxopyrrol-1-yl)phenyl]acetic acid;2-(4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)phenyl)acetic acid;4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl))-benzeneacetic acid;p-maleinimidophenylacetic acid;(4-maleimidophenyl)acetic acid;SCHEMBL6755043;KAZUDNXBQPEPGA-UHFFFAOYSA-;KAZUDNXBQPEPGA-UHFFFAOYSA-N;AC7239;MFCD06220691;AKOS000136594;BP-24412;SY247944;CS-0137855;EN300-101364;[4-(2,5-DIOXOPYRROL-1-YL)PHENYL]ACETIC ACID;Z245319778;4-(2,5-dihydro-2,5-dioxo-1h-pyrrol-1-yl)phenylethanoic acid;2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]aceticacid;InChI=1/C12H9NO4/c14-10-5-6-11(15)13(10)9-3-1-8(2-4-9)7-12(16)17/h1-6H,7H2,(H,16,17)

Suppliers and Price of 2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 11 raw suppliers

Chemical Property of 2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:231.05315777
Heavy Atom Count:17
Complexity:362

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(=O)O)N2C(=O)C=CC2=O

Technology Process of 2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid

There total 3 articles about 2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 108-31-6
maleic anhydride

: 1197-55-3
4-aminophenylacetic acid

: 91574-45-7
2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetic acid

Guidance literature:: With acetic acid; at 100 ℃; for 3h;

Reference yield: 51.0%

: 188985-07-1
(Z)-3-(4-Carboxymethyl-phenylcarbamoyl)-acrylic acid

: 91574-45-7
2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetic acid

Guidance literature:: With triethylamine; In toluene; for 2h; Heating;
DOI:10.1007/bf00807643

Reference yield:

: 1197-55-3
4-aminophenylacetic acid

: 91574-45-7
2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH / 12 h / 20 °C

2: 3.53 g / AcOH / 5 h / Heating

With acetic acid;
DOI:10.1002/anie.200601845