Cyanamide, N-[1-[4-[5-cyclopropyl-4-[[(3S)-3-[2-(trifluoromethyl)phenyl]-1-pyrrolidinyl ]carbonyl]-1H-pyrazol-1-yl]-1-piperidinyl]ethylidene]-

Base Information

• Chemical Name: Cyanamide, N-[1-[4-[5-cyclopropyl-4-[[(3S)-3-[2-(trifluoromethyl)phenyl]-1-pyrrolidinyl ]carbonyl]-1H-pyrazol-1-yl]-1-piperidinyl]ethylidene]-
• CAS No.: 916829-30-6
• Molecular Formula: C26H29F3N6O
• Molecular Weight: 498.551

Synonyms:

Chemical Property of Cyanamide, N-[1-[4-[5-cyclopropyl-4-[[(3S)-3-[2-(trifluoromethyl)phenyl]-1-pyrrolidinyl ]carbonyl]-1H-pyrazol-1-yl]-1-piperidinyl]ethylidene]-

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Technology Process of Cyanamide, N-[1-[4-[5-cyclopropyl-4-[[(3S)-3-[2-(trifluoromethyl)phenyl]-1-pyrrolidinyl ]carbonyl]-1H-pyrazol-1-yl]-1-piperidinyl]ethylidene]-

There total 1 articles about Cyanamide, N-[1-[4-[5-cyclopropyl-4-[[(3S)-3-[2-(trifluoromethyl)phenyl]-1-pyrrolidinyl ]carbonyl]-1H-pyrazol-1-yl]-1-piperidinyl]ethylidene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[5-cyclopropyl-1-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-[(S)-3-(2-trifluoromethylphenyl)]pyrrolidine hydrochloride + methyl N-cyanoacetimidate (5652-84-6) → 1-{1-[1-(1-cyanoiminoethyl)piperidin-4-yl]-5-cyclopropyl-1H-pyrazole-4-carbonyl}-[(S)-3-(2-trifluoromethylphenyl)]pyrrolidine (916829-30-6)

Guidance literature:

With triethylamine; In chloroform; at 20 - 45 ℃; for 4h;

upstream raw materials:

methyl N-cyanoacetimidate

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