2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-

Base Information

Chemical Name:2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-
CAS No.:917598-49-3
Molecular Formula:C₁₆H₁₆N₂O₂
Molecular Weight:268.315
Hs Code.:
DSSTox Substance ID:DTXSID70470291
NSC Number:730566
Wikidata:Q82298345

Synonyms:2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-;917598-49-3;DTXSID70470291;NSC730566;NSC-730566;5-hydroxy-1,3-diphenyl-hexahydropyrimidin-2-one

Suppliers and Price of 2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:268.121177757
Heavy Atom Count:20
Complexity:305

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN(C(=O)N1C2=CC=CC=C2)C3=CC=CC=C3)O

Technology Process of 2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl-

There total 4 articles about 2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1,3-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1,3-diphenyl-tetrahydro-pyrimidine-2,5-dione

: 917598-49-3
N,N'-diphenyl-5-hydroxytetrahydropyrimidin-2-one

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; for 0.333333h;
DOI:10.1080/15257770500377789

Reference yield:

: 917598-48-2
N,N'-diphenyl-5-methylenetetrahydropyrimidin-2-one

: 917598-49-3
N,N'-diphenyl-5-hydroxytetrahydropyrimidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: potassium permanganate / H₂O / 0.33 h / 0 °C

2: periodic acid / methanol; H₂O / 4 h

3: 268 mg / NaBH₄ / tetrahydrofuran / 0.33 h

With sodium tetrahydroborate; potassium permanganate; periodic acid; In tetrahydrofuran; methanol; water;
DOI:10.1080/15257770500377789

Reference yield:

: 5-hydroxy-5-hydroxymethyl-1,3-diphenyl-tetrahydro-pyrimidin-2-one

: 917598-49-3
N,N'-diphenyl-5-hydroxytetrahydropyrimidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: periodic acid / methanol; H₂O / 4 h

2: 268 mg / NaBH₄ / tetrahydrofuran / 0.33 h

With sodium tetrahydroborate; periodic acid; In tetrahydrofuran; methanol; water;
DOI:10.1080/15257770500377789