[(2R,3R,4S,5S)-5-(7-acetamido-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate

Base Information

• Chemical Name: [(2R,3R,4S,5S)-5-(7-acetamido-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate
• CAS No.: 13351-66-1
• Molecular Formula: C18H21N5O8
• Molecular Weight: 435.388
• Nikkaji Number: J2.232.293A
• Mol file: 13351-66-1.mol

Synonyms:13351-66-1;(2S,3S,4R,5R)-2-(7-Acetamido-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate;(2S,3S,4R,5R)-2-(7-Acetamido-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyldiacetate

Chemical Property of [(2R,3R,4S,5S)-5-(7-acetamido-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.46g/cm³
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 9
• Exact Mass: 435.13901265
• Heavy Atom Count: 31
• Complexity: 721

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=NC=NC2=C(NN=C21)C3C(C(C(O3)COC(=O)C)OC(=O)C)OC(=O)C
• Isomeric SMILES: CC(=O)NC1=NC=NC2=C(NN=C21)[C@H]3[C@@H]([C@@H]([C@H](O3)COC(=O)C)OC(=O)C)OC(=O)C

Technology Process of [(2R,3R,4S,5S)-5-(7-acetamido-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate

There total 2 articles about [(2R,3R,4S,5S)-5-(7-acetamido-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic anhydride (108-24-7) + formycin (57101-52-7) → 7-N-2',3',5'-tri-O-tetraacetylformycin (13351-66-1)

Guidance literature:

With pyridine; at 20 ℃; for 1h;

DOI:10.1021/jo051256w

Reference yield:

→ 7-N-2',3',5'-tri-O-tetraacetylformycin (13351-66-1)

Guidance literature:

aus Formycin I;

upstream raw materials:

acetic anhydride

formycin