4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine

Base Information

Chemical Name:4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine
CAS No.:917808-06-1
Molecular Formula:C₁₅H₁₄N₄OS₂
Molecular Weight:330.434
Hs Code.:
DSSTox Substance ID:DTXSID40575520
Wikidata:Q82464879

Synonyms:917808-06-1;4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine;SCHEMBL5815379;DTXSID40575520;4-(4-methoxyphenyl)-5-[2-(methylthio)-4-pyrimidinyl]-thiazol-2-amine

Suppliers and Price of 4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine

Chemical Property:

PSA：128.19000
LogP:3.50990
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:330.06090343
Heavy Atom Count:22
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(SC(=N2)N)C3=NC(=NC=C3)SC

Technology Process of 4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine

There total 2 articles about 4-(4-Methoxyphenyl)-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 1187242-47-2
2-bromo-1-(4-methoxyphenyl)-2-[2-(methylthio)-4-pyrimidinyl]ethanone

: 17356-08-0
thiourea

: 917808-06-1
4-(4-methoxyphenyl)-5-[2-(methylthio)-4-pyrimidinyl]thiazol-2-amine

Guidance literature:: 2-bromo-1-(4-methoxyphenyl)-2-[2-(methylthio)-4-pyrimidinyl]ethanone; thiourea; In water; for 3h; Reflux;

With sodium hydroxide; at 20 ℃;
DOI:10.1007/s00706-008-0047-9