4-Benzoylpiperidine hydrochloride

Base Information

Chemical Name:4-Benzoylpiperidine hydrochloride
CAS No.:25519-80-6
Molecular Formula:C12H15 N O . Cl H
Molecular Weight:225.718
Hs Code.:2933399090
European Community (EC) Number:681-765-3
DSSTox Substance ID:DTXSID70369131
Mol file:25519-80-6.mol

Synonyms:4-Benzoylpiperidine hydrochloride;25519-80-6;phenyl(piperidin-4-yl)methanone hydrochloride;4-Benzoylpiperidine HCL;4-Benzoylpiperidine, HCl;Methanone, phenyl-4-piperidinyl-, hydrochloride;phenyl(piperidin-4-yl)methanone;hydrochloride;Phenyl-piperidin-4-yl-methanone hydrochloride;phenyl(4-piperidyl)methanone hydrochloride;4-Benzoylpiperidinehydrochloride;4-benzoyl piperidine hydrochloride;4-benzoylpiperidine hydrogen chloride;4-benzoylpiperidinium chloride;SCHEMBL227939;4-BENZOYL PIPERIDINE HCL;DTXSID70369131;NXYKIFZJQXOUJS-UHFFFAOYSA-N;phenyl(piperidin-4-yl)methanone HCl;CCG-50354;MFCD00066982;AKOS015912990;AB02723;PS-7774;phenyl (4-piperidyl)methanone hydrochloride;phenyl(4-piperidinyl)methanone hydrochloride;CS-0112314;FT-0641387;FT-0662611;4-benzoylpiperidine hydrochloride, AldrichCPR;EN300-30359;A817892;J-016034;SR-01000639738-1;F0001-0857

Suppliers and Price of 4-Benzoylpiperidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-BenzoylpiperidineHydrochloride
250mg
$ 345.00

TRC
4-BenzoylpiperidineHydrochloride
100mg
$ 140.00

SynQuest Laboratories
Phenyl(piperidin-4-yl)methanone hydrochloride
5 g
$ 120.00

SynQuest Laboratories
Phenyl(piperidin-4-yl)methanone hydrochloride
1 g
$ 29.00

SynQuest Laboratories
Phenyl(piperidin-4-yl)methanone hydrochloride
10 g
$ 232.00

Medical Isotopes, Inc.
Phenyl(piperidin-4-yl)methanoneHCl
1 g
$ 1600.00

Matrix Scientific
Phenyl(piperidin-4-yl)methanone hydrochloride 97%
1g
$ 130.00

Matrix Scientific
Phenyl(piperidin-4-yl)methanone hydrochloride 97%
10g
$ 924.00

Labseeker
4-BENZOYLPIPERIDINEHYDROCHLORIDE 95
5g
$ 885.00

Crysdot
Phenyl(piperidin-4-yl)methanonehydrochloride 98%
25g
$ 360.00

Total 27 raw suppliers

Chemical Property of 4-Benzoylpiperidine hydrochloride

Chemical Property:

Vapor Pressure:0.000589mmHg at 25°C
Melting Point:95-97oC
Boiling Point:310.7°Cat760mmHg
Flash Point:125.3°C
PSA：29.10000
Density:g/cm³
LogP:2.99970
Storage Temp.:-20?C Freezer
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:225.0920418
Heavy Atom Count:15
Complexity:191

Purity/Quality:

99%, ^*data from raw suppliers

4-BenzoylpiperidineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)C2=CC=CC=C2.Cl
Uses A synthetic intermediate in the preparation of CNS depressants.

Technology Process of 4-Benzoylpiperidine hydrochloride

There total 6 articles about 4-Benzoylpiperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 193217-39-9
1-(t-butoxycarbonyl)-4-(benzoyl)piperidine

: 25519-80-6
4-(benzoyl)piperidine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 18 - 25 ℃; for 0.5h;

Reference yield:

: 25519-79-3
1-(4-benzoylpiperidin-1-yl)ethanone

: 25519-80-6
4-(benzoyl)piperidine hydrochloride

Guidance literature:: With hydrogenchloride; water; In tetrahydrofuran; for 10h; Reflux;
DOI:10.1016/j.bmcl.2015.09.072

Reference yield:

: 25503-90-6
1-acetyl-piperidine-4-carboxylic acid

: 25519-80-6
4-(benzoyl)piperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 4 h / 0 - 60 °C

2: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C

3: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux

With hydrogenchloride; aluminum (III) chloride; thionyl chloride; water; N,N-dimethyl-formamide; In tetrahydrofuran; 1,2-dichloro-ethane; 2: |Friedel-Crafts Acylation;
DOI:10.1016/j.bmcl.2015.09.072