3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL

Base Information

Chemical Name:3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL
CAS No.:918138-95-1
Molecular Formula:C17H26OSi
Molecular Weight:274.478
Hs Code.:
DSSTox Substance ID:DTXSID10587392
Nikkaji Number:J2.404.253G

Synonyms:3-[DIMETHYL(PHENYL)SILYL]NON-4-YN-3-OL;918138-95-1;DTXSID10587392

Suppliers and Price of 3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL

Chemical Property:

PSA：20.23000
LogP:3.89580
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:274.175291983
Heavy Atom Count:19
Complexity:330

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC#CC(CC)(O)[Si](C)(C)C1=CC=CC=C1

Technology Process of 3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL

There total 1 articles about 3-[Dimethyl(phenyl)silyl]non-4-YN-3-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 693-02-7
hex-1-yne

: 128084-44-6
1-(dimethyl(phenyl)silyl)propan-1-one

: 918138-95-1
3-(dimethyl(phenyl)silyl)non-4-yn-3-ol

Guidance literature:: hex-1-yne; With ethylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h;

1-(dimethyl(phenyl)silyl)propan-1-one; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 3h;
DOI:10.1021/ja0653674

Reference yield:

: 918138-95-1
3-(dimethyl(phenyl)silyl)non-4-yn-3-ol

: (Z)-4-((4-chlorophenyl)(hydroxy)methyl)non-4-en-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: n-BuLi / tetrahydrofuran / 0.17 h / 0 °C

2: 1,3-di(2,6-diisopropylphenyl)-1,3-dihydro-imidazol-2-ylidene / tetrahydrofuran / -78 °C

With n-butyllithium; In tetrahydrofuran;
DOI:10.1021/ol0710515

Reference yield:

: 918138-95-1
3-(dimethyl(phenyl)silyl)non-4-yn-3-ol

: (Z)-4-(hydroxy(4-methoxyphenyl)methyl)non-4-en-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: n-BuLi / tetrahydrofuran / 0.17 h / 0 °C

2: 1,3-di(2,6-diisopropylphenyl)-1,3-dihydro-imidazol-2-ylidene / tetrahydrofuran / -78 °C

With n-butyllithium; In tetrahydrofuran;
DOI:10.1021/ol0710515