Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Base Information

Chemical Name:Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate
CAS No.:918145-25-2
Molecular Formula:C₁₄H₁₁NO₂S
Molecular Weight:257.313
Hs Code.:
DSSTox Substance ID:DTXSID70589610
Wikidata:Q82483077

Synonyms:methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate;918145-25-2;DTXSID70589610;BBL021934;STK894651;AKOS005144504;methyl6-methylthieno[2,3-b]quinoline-2-carboxylate

Suppliers and Price of Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl6-methylthieno[2,3-b]quinoline-2-carboxylate 97%
1g
$ 452.00

American Custom Chemicals Corporation
METHYL 6-METHYLTHIENO[2,3-B]QUINOLINE-2-CARBOXYLATE 95.00%
5MG
$ 504.65

Total 1 raw suppliers

Chemical Property of Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Chemical Property:

PSA：67.43000
LogP:3.54450
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:257.05104977
Heavy Atom Count:18
Complexity:336

Purity/Quality:: Methyl6-methylthieno[2,3-b]quinoline-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CC3=C(N=C2C=C1)SC(=C3)C(=O)OC

Technology Process of Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

There total 4 articles about Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1013105-64-0
methyl [(3-formyl-6-methylquinolin-2-yl)thio]acetate

: 918145-25-2
methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1080/10426500601088846

Reference yield:

: 73568-27-1
2-chloro-6-methylquinoline-3-carbaldehyde

: 918145-25-2
methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: Na₂S; HCl / ethanol / Heating

2: K₂CO₃ / acetone / Heating

3: 73 percent / POCl₃ / Heating

4: 76 percent / dimethylformamide / 20 °C

With hydrogenchloride; sodium sulfide; potassium carbonate; trichlorophosphate; In ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1080/10426500601088846

Reference yield:

: 887922-68-1
2-mercapto-6-methylquinoline-3-carbaldehyde

: 918145-25-2
methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / Heating

2: 73 percent / POCl₃ / Heating

3: 76 percent / dimethylformamide / 20 °C

With potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; acetone;
DOI:10.1080/10426500601088846