4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol

Base Information

Chemical Name:4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol
CAS No.:918160-50-6
Molecular Formula:C13H19NO3S
Molecular Weight:269.365
Hs Code.:
DSSTox Substance ID:DTXSID30569938

Synonyms:918160-50-6;4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol;DTXSID30569938

Suppliers and Price of 4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol

Chemical Property:

PSA：65.76000
LogP:2.54920
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:269.10856464
Heavy Atom Count:18
Complexity:355

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC2CCCCO

Technology Process of 4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol

There total 4 articles about 4-[1-(4-Methylbenzene-1-sulfonyl)aziridin-2-yl]butan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 176516-06-6
2-but-3-enyl-1-(toluene-4-sulfonyl)aziridine

: 918160-50-6
4-[1-(toluene-4-sulfonyl)aziridin-2-yl]butan-1-ol

Guidance literature:: 2-but-3-enyl-1-(toluene-4-sulfonyl)aziridine; With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; at 20 ℃; for 4h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1021/ja0660756

Reference yield: 75.0%

: 2-[4-(tert-Butyl-dimethyl-silanyloxy)-butyl]-1-(toluene-4-sulfonyl)-aziridine

: 918160-50-6
4-[1-(toluene-4-sulfonyl)aziridin-2-yl]butan-1-ol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/0040-4039(95)00608-F

Reference yield:

: 592-42-7
1,5-Hexadien

: 918160-50-6
4-[1-(toluene-4-sulfonyl)aziridin-2-yl]butan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 65 percent / Cu(OTf)2 / acetonitrile / 0.25 h / 20 °C

2.1: 9-BBN / tetrahydrofuran / 4 h / 20 °C

2.2: 89 percent / aqueous sodium hydroxide; aqueous hydrogen peroxide / tetrahydrofuran / 2 h / 20 °C

With 9-borabicyclo[3.3.1]nonane dimer; copper(II) bis(trifluoromethanesulfonate); In tetrahydrofuran; acetonitrile;
DOI:10.1021/ja0660756