(-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine

Base Information

Chemical Name:(-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine
CAS No.:81202-76-8
Molecular Formula:C19H21N
Molecular Weight:263.3767
Hs Code.:
ChEMBL ID:CHEMBL166738
Mol file:81202-76-8.mol

Synonyms:BRN 4690809;BRN 6062753;1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-1-methyl-5-phenyl-, (4a-alpha,5-alpha,9b-alpha)-;(-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine;(-)-2,3,4,4a,5,9b-Hexahydro-1-methyl-5-phenyl-1H-indeno(1,2-b)pyridine;1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-1-methyl-5-phenyl-, (-)-;81202-76-8;107035-08-5;CHEMBL166738;LS-81932;LS-81935

Suppliers and Price of (-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine

Chemical Property:

Vapor Pressure:8.24E-06mmHg at 25°C
Melting Point:81 - 83 °C (diisopropyl ether)
Boiling Point:374.6°C at 760 mmHg
Flash Point:162.2°C
PSA：3.24000
Density:1.071g/cm³
LogP:4.15290
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:263.167399674
Heavy Atom Count:20
Complexity:333

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCCC2C1C3=CC=CC=C3C2C4=CC=CC=C4
Isomeric SMILES:CN1CCC[C@H]2[C@@H]1C3=CC=CC=C3[C@@H]2C4=CC=CC=C4

Technology Process of (-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine

There total 8 articles about (-)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno(1,2-b)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 88763-06-8
(4aR,5R,9bR)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

: 81202-76-8
(4aS,5R,9bS)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: With potassium hydroxide; In butan-1-ol; for 14h; Heating;

Reference yield:

: 10413-00-0
5-oxo-5-phenylpentanenitrile

: 81202-76-8
(4aS,5R,9bS)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / 85percentiger Phosphorsaeure, Phosphorpentoxid / 1 h / 80 °C

2: 69 percent / hydrogen / Raney-Nickel

3: 1.) Natriumamid / 1.) Toluol, zweienhalb Stunden, Rueckfluss, 2.) 4 Stunden, Rueckfluss

4: 44 percent / Lithiumaluminiumhydrid / diethyl ether / 6 h / Heating

5: 84 percent / Kaliumhydroxid / butan-1-ol / 14 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; phosphoric acid; hydrogen; phosphorus pentoxide; sodium amide; nickel; In diethyl ether; butan-1-ol;

Reference yield:

: 34502-63-1
6-Phenyl-1,2,3,4-tetrahydropyridin-2-on

: 81202-76-8
(4aS,5R,9bS)-1-Methyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / 85percentiger Phosphorsaeure, Phosphorpentoxid / 1 h / 80 °C

2: 69 percent / hydrogen / Raney-Nickel

3: 1.) Natriumamid / 1.) Toluol, zweienhalb Stunden, Rueckfluss, 2.) 4 Stunden, Rueckfluss

4: 44 percent / Lithiumaluminiumhydrid / diethyl ether / 6 h / Heating

5: 84 percent / Kaliumhydroxid / butan-1-ol / 14 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; phosphoric acid; hydrogen; phosphorus pentoxide; sodium amide; nickel; In diethyl ether; butan-1-ol;