3-Oxazolidinecarboxylic acid, 4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-

Base Information

Chemical Name:3-Oxazolidinecarboxylic acid, 4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-
CAS No.:918304-95-7
Molecular Formula:C40H53IN2O6Si
Molecular Weight:812.861
Hs Code.:

3-Oxazolidinecarboxylic acid,
4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb
onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-,
1,1-dimethylethyl ester, (4S)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Oxazolidinecarboxylic acid, 4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-

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MSDS Files:: SDS file from LookChem

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Technology Process of 3-Oxazolidinecarboxylic acid, 4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-

There total 1 articles about 3-Oxazolidinecarboxylic acid, 4-[[3-[(1Z)-1-[[(2-iodophenyl)[[2-(trimethylsilyl)ethoxy]methyl]amino]carb onyl]-1-propen-1-yl]-4-(phenylmethoxy)phenyl]methyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 918304-64-0
tert-butyl (4S)-4-[4-benzyloxy-3-((Z)-1-(2-iodophenylcarbamoyl)prop-1-enyl)-benzyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 918304-95-7
tert-butyl (4S)-4-[4-benzyloxy-3-((Z)-1-(N-((2-(trimethylsilyl)ethoxy)methyl)-N-2-iodophenylcarbamoyl)prop-1-enyl)-benzyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 14h;
DOI:10.1039/b609604b

Reference yield: 77.0%

: 918304-95-7
tert-butyl (4S)-4-[4-benzyloxy-3-((Z)-1-(N-((2-(trimethylsilyl)ethoxy)methyl)-N-2-iodophenylcarbamoyl)prop-1-enyl)-benzyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 918304-65-1
tert-butyl (4S)-4-{4-benzyloxy-3-[2-oxo-1-((2-trimethylsilyl)ethoxy)methyl-3-vinyl-2,3-dihydro-1H-indol-3-yl]benzyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Guidance literature:: With silver orthophosphate; triphenylphosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In N,N-dimethyl acetamide; at 90 ℃; for 36h;
DOI:10.1039/b609604b