Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino-

Base Information

Chemical Name:Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino-
CAS No.:5782-95-6
Molecular Formula:C₂₃H₂₆N₂O₂
Molecular Weight:362.472
Hs Code.:
DSSTox Substance ID:DTXSID70206537
Nikkaji Number:J55.109K
ChEMBL ID:CHEMBL3185768

Synonyms:BRN 0445700;5782-95-6;ACRIDINE, 1,2,3,4-TETRAHYDRO-9-(2-(3,4-DIMETHOXYPHENYL)ETHYL)AMINO-;4-(2-(3,4,-Dimethoxyphenyl)ethyl)amino-2,3-tetramethylenequinoline;Acridine, 9-(2-(3,4-dimethoxyphenyl)ethyl)amino-1,2,3,4-tetrahydro-;Phenethylamine, 3,4-dimethoxy-N-(1,2,3,4-tetrahydro-9-acridinyl)-;CHEMBL3185768;DTXSID70206537;BDBM199196;KUC109856N;KSC-28-25-1;9-Acridinamine, N-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3,4-tetrahydro-;N-(3,4-Dimethoxyphenethyl)-1,2,3,4-tetrahydroacridin-9-amine (11a);N-[2-(3,4-Dimethoxyphenyl)ethyl]-1,2,3,4-tetrahydro-9-acridinamine

Suppliers and Price of Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino-

Chemical Property:

Vapor Pressure:5.97E-13mmHg at 25°C
Boiling Point:568.8°Cat760mmHg
Flash Point:297.8°C
Density:1.175g/cm³
XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:362.199428076
Heavy Atom Count:27
Complexity:460

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCNC2=C3CCCCC3=NC4=CC=CC=C42)OC

Technology Process of Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino-

There total 3 articles about Acridine, 1,2,3,4-tetrahydro-9-(2-(3,4-dimethoxyphenyl)ethyl)amino- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 5396-30-5
9-chloro-1,2,3,4-tetrahydroacridine

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 5782-95-6
N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrahydroacridin-9-amine

Guidance literature:: With sodium iodide; In butan-1-ol; at 150 ℃; for 4.5h;
DOI:10.1111/cbdd.12800

Reference yield:

: 552-16-9,104810-18-6
ortho-nitrobenzoic acid

: 5782-95-6
N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrahydroacridin-9-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrazine hydrate; palladium on activated carbon / ethanol / 1.5 h / 0 - 80 °C / Inert atmosphere

2.1: trichlorophosphate / 0.08 h / 0 °C

2.2: 2.5 h / 120 °C / Molecular sieve

3.1: sodium iodide / butan-1-ol / 4.5 h / 150 °C

With palladium on activated carbon; hydrazine hydrate; sodium iodide; trichlorophosphate; In ethanol; butan-1-ol;
DOI:10.1111/cbdd.12800

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 5782-95-6
N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrahydroacridin-9-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.08 h / 0 °C

1.2: 2.5 h / 120 °C / Molecular sieve

2.1: sodium iodide / butan-1-ol / 4.5 h / 150 °C

With sodium iodide; trichlorophosphate; In butan-1-ol;
DOI:10.1111/cbdd.12800