2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid

Base Information

Chemical Name:2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid
CAS No.:34418-48-9
Molecular Formula:C10H8 N2 O2 S
Molecular Weight:220.252
Hs Code.:2934100090
European Community (EC) Number:623-796-7
DSSTox Substance ID:DTXSID50187991
Nikkaji Number:J59.604C
Wikidata:Q83059755
ChEMBL ID:CHEMBL1600925
Mol file:34418-48-9.mol

Synonyms:34418-48-9;4-methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxylic acid;2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid;4-Methyl-2-(pyridin-2-yl)thiazole-5-carboxylic acid;2-(2-Pyridyl)-4-methyl-thiazole-5-Carboxylic Acid;4-Methyl-2-(Pyridin-2-Yl)-1,3-Thiazole-5-Carboxylic Acid;4-Methyl-2-(2-pyridyl)-5-thiazolecarboxylic acid;5-Thiazolecarboxylic acid, 4-methyl-2-(2-pyridyl)-;4-Methyl-2-pyridin-2-yl-thiazole-5-carboxylic acid;MFCD01316364;4-Methyl-2-(2-pyridinyl)-5-thiazolecarboxylic acid;Oprea1_650936;MLS000716739;SCHEMBL596082;4-Methyl-2-(pyridin-2-yl)thiazole-5-carboxylicacid;CHEMBL1600925;4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxylic acid;DTXSID50187991;HMS2655G20;BBL009920;STK711087;AKOS000273783;2G-307S;NCGC00245438-01;SMR000278256;LS-150891;CS-0064247;FT-0678828;EN300-14267;F13735;4-Methyl-2-(2-pyridyl)thiazole-5-carboxylic acid;A874982;J-019593;J-515704;Z99599550;2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid, 96%;F3249-0138

Suppliers and Price of 2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxylicAcid
500mg
$ 45.00

Sigma-Aldrich
2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid 96%
1g
$ 51.00

Matrix Scientific
2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid 97%
5g
$ 139.00

Crysdot
4-Methyl-2-(pyridin-2-yl)thiazole-5-carboxylicacid 97%
25g
$ 473.00

Chemenu
2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid 97%
25g
$ 447.00

Cayman Chemical
2-(2-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid ≥98%
500mg
$ 44.00

Cayman Chemical
2-(2-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid ≥98%
250mg
$ 25.00

Cayman Chemical
2-(2-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid ≥98%
100mg
$ 11.00

Cayman Chemical
2-(2-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid ≥98%
1g
$ 66.00

Atlantic Research Chemicals
4-Methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxylicacid 95%
250mgs:
$ 116.64

Total 26 raw suppliers

Chemical Property of 2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid

Chemical Property:

Vapor Pressure:3.71E-09mmHg at 25°C
Melting Point:221-226 °C (D)
Boiling Point:457.3°Cat760mmHg
Flash Point:230.4°C
PSA：91.32000
Density:1.381g/cm³
LogP:2.21170
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:220.03064868
Heavy Atom Count:15
Complexity:250

Purity/Quality:

99%, ^*data from raw suppliers

4-Methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC(=N1)C2=CC=CC=N2)C(=O)O
Description 2-(2-pyridyl)-4-methyl-Thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

Technology Process of 2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid

There total 3 articles about 2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.2%

: 2-pyridyl-4-methylthiazole-5-carboxylic acid ethyl ester

: 34418-48-9
2-(2-pyridyl)-4-methylimidazole-5-carboxylic acid

Guidance literature:: With methanol; sodium hydroxide; at 90 ℃; for 5h;

Reference yield:

: 4621-66-3
thionicotinamide

: 34418-48-9
2-(2-pyridyl)-4-methylimidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 2 h / 75 °C

2: methanol; sodium hydroxide / 5 h / 90 °C

With methanol; sodium hydroxide; In ethanol;

Reference yield:

: 98-92-0,1255150-40-3
nicotinamide

: 34418-48-9
2-(2-pyridyl)-4-methylimidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: tetraphosphorus decasulfide / tetrahydrofuran / 3 h / 70 °C

2: ethanol / 2 h / 75 °C

3: methanol; sodium hydroxide / 5 h / 90 °C

With methanol; tetraphosphorus decasulfide; sodium hydroxide; In tetrahydrofuran; ethanol;