1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-

Base Information

Chemical Name:1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-
CAS No.:92972-83-3
Molecular Formula:C14H12N4O3
Molecular Weight:284.2701
Hs Code.:
DSSTox Substance ID:DTXSID20239214
Wikidata:Q83121566

Synonyms:BRN 4538116;1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-;92972-83-3;5-(5-(4-Methylphenyl)-2-furyl)-1-tetrazoylacetic acid;5-(5-(4-Methylphenyl)-2-furanyl)-1H-tetrazole-1-acetic acid;DTXSID20239214;LS-149071

Suppliers and Price of 1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-

Chemical Property:

Vapor Pressure:6.62E-13mmHg at 25°C
Boiling Point:549.4°Cat760mmHg
PKA:2.58±0.10(Predicted)
Flash Point:286.1°C
PSA：94.04000
Density:1.43g/cm³
LogP:1.99310
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:284.09094026
Heavy Atom Count:21
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CC=C(O2)C3=NN=NN3CC(=O)O

Technology Process of 1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)-

There total 5 articles about 1H-Tetrazole-1-acetic acid, 5-(5-(4-methylphenyl)-2-furanyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 92973-12-1
[5-(5-p-Tolyl-furan-2-yl)-tetrazol-1-yl]-acetic acid ethyl ester

: 92972-83-3
[5-(5-p-Tolyl-furan-2-yl)-tetrazol-1-yl]-acetic acid

Guidance literature:: With hydrogenchloride; potassium hydroxide; In methanol; water; for 1h; Heating;
DOI:10.1135/cccc19841505

Reference yield:

: 52938-98-4
5-p-tolyl-furan-2-carboxylic acid

: 92972-83-3
[5-(5-p-Tolyl-furan-2-yl)-tetrazol-1-yl]-acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: SOCl₂ / DMF / 0.67 h / Heating

2: 90 percent / triethylamine / CHCl₃ / 1.) -5 to 0 deg C, 30 min; 2.) r.t., 1 h

3: PCl₅ / benzene / 0.25 h / 75 °C

4: sodium azide / dimethylformamide / 0.5 h

5: 95 percent / 1.) 0.75M KOH, 2.) 15percent HCl / methanol; H₂O / 1 h / Heating

With hydrogenchloride; potassium hydroxide; thionyl chloride; sodium azide; phosphorus pentachloride; triethylamine; DMF; In methanol; chloroform; water; N,N-dimethyl-formamide; benzene;
DOI:10.1135/cccc19841505

Reference yield:

: 60336-00-7
5-p-tolyl-furan-2-carbonyl chloride

: 92972-83-3
[5-(5-p-Tolyl-furan-2-yl)-tetrazol-1-yl]-acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / triethylamine / CHCl₃ / 1.) -5 to 0 deg C, 30 min; 2.) r.t., 1 h

2: PCl₅ / benzene / 0.25 h / 75 °C

3: sodium azide / dimethylformamide / 0.5 h

4: 95 percent / 1.) 0.75M KOH, 2.) 15percent HCl / methanol; H₂O / 1 h / Heating

With hydrogenchloride; potassium hydroxide; sodium azide; phosphorus pentachloride; triethylamine; In methanol; chloroform; water; N,N-dimethyl-formamide; benzene;
DOI:10.1135/cccc19841505