2-Propyn-1-ol, 3-(4-ethylphenyl)-

Base Information

• Chemical Name: 2-Propyn-1-ol, 3-(4-ethylphenyl)-
• CAS No.: 918625-92-0
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol file: 918625-92-0.mol

Synonyms:3-(4-ethylphenyl)-2-propyne-1-ol;1-(4-ethylphenyl)-1-propyn-3-ol;2-Propyn-1-ol,3-(4-ethylphenyl);3-(4-ethylphenyl)-prop-2-yn-1-ol;3-(4-ethylphenyl)-2-propyn-1-ol;

Chemical Property of 2-Propyn-1-ol, 3-(4-ethylphenyl)-

Chemical Property:

• Boiling Point: 270.2±33.0 °C(Predicted)
• PSA: 20.23000
• Density: 1.04±0.1 g/cm3(Predicted)
• LogP: 1.59280

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Ethyl-phenyl)-prop-2-yn-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propyn-1-ol, 3-(4-ethylphenyl)-

There total 2 articles about 2-Propyn-1-ol, 3-(4-ethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4-ethyl-1-iodobenzene (25309-64-2) + propargyl alcohol (107-19-7) → 3-(4-ethylphenyl)-prop-2-yn-1-ol (918625-92-0)

Guidance literature:

With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; at 20 ℃; for 2h;

DOI:10.1002/adsc.200505238

Reference yield:

propargyl alcohol (107-19-7) → 3-(4-ethylphenyl)-prop-2-yn-1-ol (918625-92-0)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine;

DOI:10.1016/S0960-894X(01)00253-0

Reference yield: 92.0%

(E)-1,5-diphenylpent-2-enyl acetate (1210512-37-0) + 3-(4-ethylphenyl)-prop-2-yn-1-ol (918625-92-0) → C28H28O

Guidance literature:

With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold (I); In dichloromethane; at 25 ℃; for 2h; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol1012923

upstream raw materials:

propargyl alcohol

4-ethyl-1-iodobenzene

Downstream raw materials:

3-(4-ethylphenyl)propan-1-ol

ediethyl 4-(4-ethylphenyl)-5-formylfuran-2,3-dicarboxylate

diethyl 4-(4-ethylphenyl)-5-methylfuran-2,3-dicarboxylate