Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-

Base Information

Chemical Name:Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-
CAS No.:918642-61-2
Molecular Formula:C11H10FNO3
Molecular Weight:223.204
Hs Code.:

Synonyms:1-(2-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid;Cyclopropanecarboxylic acid,1-[[(2-fluorophenyl)amino]carbonyl];

Suppliers and Price of Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 14 raw suppliers

Chemical Property of Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-

Chemical Property:

Boiling Point:463.4±30.0 °C(Predicted)
PSA：69.89000
Density:1.521±0.06 g/cm3(Predicted)
LogP:2.27850

Purity/Quality:: 95%+HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-(2-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid is used in the preparation of 1,1-cyclopropyl diamide derivatives.

Technology Process of Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-

There total 4 articles about Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 918642-61-2
1-((2-fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid

Guidance literature:

Reference yield: 54.0%

: 348-54-9
2-Fluoroaniline

: 918642-61-2
1-((2-fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid

Guidance literature:: cyclopropane-1,1-dicarboxylic acid; With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

With thionyl chloride; In tetrahydrofuran; at 0 ℃; for 0.5h;

2-Fluoroaniline; With hydrogenchloride; sodium hydroxide; water; more than 3 stages;

Reference yield: 45.0%

: 348-54-9
2-Fluoroaniline

: 598-10-7
cyclopropane-1,1-dicarboxylic acid

: 918642-61-2
1-((2-fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid

Guidance literature:: cyclopropane-1,1-dicarboxylic acid; With thionyl chloride; In Isopropyl acetate; at 0 - 20 ℃; for 6h;

2-Fluoroaniline; With triethylamine; In Isopropyl acetate; for 3h;
DOI:10.1016/j.bmcl.2017.06.041