Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-

Base Information

Chemical Name:Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-
CAS No.:91870-65-4
Molecular Formula:C17H14N2O2S
Molecular Weight:310.37000
Hs Code.:
DSSTox Substance ID:DTXSID30387013
Nikkaji Number:J1.212.921A

Synonyms:5'-methyl-3'-phenyl-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione;91870-65-4;Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-;CBMicro_009755;Oprea1_154405;DTXSID30387013;HMS1691L04;SMSF0010515;CCG-21130;STK024832;AKOS000550496;CB12590;BIM-0009803.P001;EU-0046086;SR-01000500481;SR-01000500481-1;5'-Methyl-3'-phenylspiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione

Suppliers and Price of Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-

Chemical Property:

PSA：78.20000
LogP:3.11010
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:310.07759887
Heavy Atom Count:22
Complexity:491

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(=O)N(C2(S1)C3=CC=CC=C3NC2=O)C4=CC=CC=C4

Technology Process of Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl-

There total 6 articles about Spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione, 5'-methyl-3'-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 79-42-5
2-mercaptopropanoic acid

: 62-53-3
aniline

: 91870-65-4
5'-methyl-3'-phenylspiro<3H-indole-3,2'-thiazolidine>-2,4'(1H)-dione

Guidance literature:: With cetyltrimethylammonim bromide; In water; Sonication; Combinatorial reaction / High throughput screening (HTS);
DOI:10.1039/c0gc00863j

Reference yield: 63.0%

: 33828-98-7,101671-27-6
3-phenylimino-2-indolinone

: 79-42-5
2-mercaptopropanoic acid

: 91870-65-4
5'-methyl-3'-phenylspiro<3H-indole-3,2'-thiazolidine>-2,4'(1H)-dione

Guidance literature:: In ethanol; microwave irradiation;
DOI:10.1080/10426509808035679

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 91870-65-4
5'-methyl-3'-phenylspiro<3H-indole-3,2'-thiazolidine>-2,4'(1H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: glacial acetic acid / ethanol / 0.5 h / Heating

2: 57 percent / toluene / 10 h / Heating

With acetic acid; In ethanol; toluene;
DOI:10.1002/jhet.5570210203