Technology Process of Benzamide,
N-[9-[2-amino-3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-9H-purin-6
-yl]-
There total 7 articles about Benzamide,
N-[9-[2-amino-3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-9H-purin-6
-yl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(+/-)-N-(9-{2-azido-3-[(4-methoxytrityl)oxy]propyl}-9H-purin-6-yl)benzamide;
With
triphenylphosphine;
In
tetrahydrofuran;
With
water;
In
tetrahydrofuran;
for 3h;
Heating;
DOI:10.1135/cccc20060015
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 21.43 g / pyridine / 2 h
2.1: NaN3 / dimethylformamide / 100 °C
3.1: 7.44 g / NaOH / methanol
4.1: 45 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 20 °C
5.1: 85 percent / pyridine / 20 °C
6.1: Ph3P / tetrahydrofuran
6.2: 94 percent / H2O / tetrahydrofuran / 3 h / Heating
With
pyridine; sodium hydroxide; sodium azide; di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
4.1: Mitsunobu reaction;
DOI:10.1135/cccc20060015
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 45 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 20 °C
2.1: 85 percent / pyridine / 20 °C
3.1: Ph3P / tetrahydrofuran
3.2: 94 percent / H2O / tetrahydrofuran / 3 h / Heating
With
pyridine; di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
1.1: Mitsunobu reaction;
DOI:10.1135/cccc20060015
![(+/-)-N-(9-{2-azido-3-[(4-methoxytrityl)oxy]propyl}-9H-purin-6-yl)benzamide](/Databaselist/images/loading.webp)
