1,3-dichloro-7-nitro-9H-fluorene

Base Information

• Chemical Name: 1,3-dichloro-7-nitro-9H-fluorene
• CAS No.: 92961-03-0
• Molecular Formula: C₁₃H₇Cl₂NO₂
• Molecular Weight: 280.11
• NSC Number: 80155
• DSSTox Substance ID: DTXSID30292052
• Wikidata: Q82030186
• Mol file: 92961-03-0.mol

Synonyms:92961-03-0;1,3-dichloro-7-nitro-9H-fluorene;NSC80155;NCIOpen2_004208;DTXSID30292052;NSC-80155

Chemical Property of 1,3-dichloro-7-nitro-9H-fluorene

Chemical Property:

• Vapor Pressure: 3.81E-07mmHg at 25°C
• Boiling Point: 428.4°Cat760mmHg
• Flash Point: 212.9°C
• Density: 1.521g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 278.9853839
• Heavy Atom Count: 18
• Complexity: 346

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C2=C(C=CC(=C2)[N+](=O)[O-])C3=C1C(=CC(=C3)Cl)Cl

Technology Process of 1,3-dichloro-7-nitro-9H-fluorene

There total 4 articles about 1,3-dichloro-7-nitro-9H-fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3',5'-dichloro-4-nitro-biphenyl-2-yl)-methanol → 1,3-Dichlor-7-nitro-fluoren (92961-03-0)

Guidance literature:

With PPA; at 110 ℃;

DOI:10.1016/j.bmcl.2005.08.003

Reference yield:

2-acetylamino-7-nitrofluorene (72570-99-1) → 1,3-Dichlor-7-nitro-fluoren (92961-03-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Cl₂, FeCl₃

2: aq. HCl

3: (i) NaNO₂, aq. HCl, (ii) H₃PO₂

With hydrogenchloride; chlorine; iron(III) chloride;

DOI:10.1021/jm00331a008

Reference yield:

N-2-(1.3-Dichlor-7-nitro-fluorenyl)-acetamid (899-87-6) → 1,3-Dichlor-7-nitro-fluoren (92961-03-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl

2: (i) NaNO₂, aq. HCl, (ii) H₃PO₂

With hydrogenchloride;

DOI:10.1021/jm00331a008

upstream raw materials:

1.3-Dichlor-7-nitro-2-fluorenamin

2-acetylamino-7-nitrofluorene

N-2-(1.3-Dichlor-7-nitro-fluorenyl)-acetamid

Downstream raw materials:

1,3-Dichlor-7-nitro-9-oxo-fluoren