6-(trifluoromethyl)-7H-purine

Base Information

Chemical Name:6-(trifluoromethyl)-7H-purine
CAS No.:2268-11-3
Molecular Formula:C6H3 F3 N4
Molecular Weight:188.11
Hs Code.:
NSC Number:515791
DSSTox Substance ID:DTXSID80421678
Nikkaji Number:J457.088J
Mol file:2268-11-3.mol

Synonyms:6-(trifluoromethyl)-7H-purine;2268-11-3;6-(TRIFLUOROMETHYL)-9H-PURINE;SCHEMBL2934090;6-(TRIFLUOROMETHYL)PURINE;DTXSID80421678;RPGVDXOVVBWOIH-UHFFFAOYSA-N;NSC515791;AKOS006323055;AB64228;NSC-515791

Suppliers and Price of 6-(trifluoromethyl)-7H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6-(trifluoromethyl)-7H-purine

Chemical Property:

Vapor Pressure:1.63mmHg at 25°C
Boiling Point:174.3°Cat760mmHg
Flash Point:59.2°C
Density:1.79g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:188.03098060
Heavy Atom Count:13
Complexity:195

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=NC=NC(=C2N1)C(F)(F)F

Technology Process of 6-(trifluoromethyl)-7H-purine

There total 4 articles about 6-(trifluoromethyl)-7H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 9-(Tetrahydropyran-2-yl)-6-(trifluoromethyl)purine

: 2268-11-3
6-(Trifluoromethyl)purine

Guidance literature:: With Dowex 50 X 8 (H(+)); water; In methanol; for 1h; Heating;
DOI:10.1135/cccc19990229

Reference yield:

: 776-60-3
N-(6-oxo-4-trifluoromethyl-1,6-dihydro-pyrimidin-5-yl)-formamide

: 2268-11-3
6-trifluoromethyl-7(9)H-purine

Guidance literature:: With trichlorophosphate; und Behandeln des Reaktionsprodukts mit aethanol.NH₃ und Erhitzen des Reaktionsprodukts in Formamid;
DOI:10.1021/ja01554a041

Reference yield:

: 2253-28-3
5-amino-6-trifluoromethyl-3H-pyrimidin-4-one

: 2268-11-3
6-trifluoromethyl-7(9)H-purine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid anhydride

2: POCl₃ / und Behandeln des Reaktionsprodukts mit aethanol.NH₃ und Erhitzen des Reaktionsprodukts in Formamid

With acetic anhydride; trichlorophosphate;
DOI:10.1021/ja01554a041